The Financial and Emotional Impact of Atopic Dermatitis on Children and Their Families

Filanovsky, Michelle G.; Pootongkam, Suwimon; Tamburro, Joan; Smith, Mary C.; Ganocy, Stephen J.; Nedorost, Susan T.

doi:10.1016/j.jpeds.2015.10.077

Cited by 73 publications

(75 citation statements)

References 30 publications

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“…Medical care costs specifically for pediatric AD were conservatively estimated at $364 million in 1993, a figure likely much greater now due to inflation of medical costs and an increased prevalence of AD . Both prescription medications and over‐the‐counter moisturizing options are necessary for AD treatment and prevention of flares, so costs of medical care alone for AD can become very high, particularly when patients’ symptoms are not well controlled …”

Section: Methodsmentioning

confidence: 99%

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The impact of pediatric atopic dermatitis on families: A review

Yang

Beck

Sekhon

et al. 2018

Pediatric Dermatology

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Background Atopic dermatitis (AD) is an extremely common childhood disease, with considerable impact on the quality of life of affected children and their families. While pruritus is the hallmark symptom of this disease, AD has been well‐documented to impact patients beyond physical symptoms, resulting in behavior problems, mood disorders, and sleep disturbance. Objective This literature review outlines how atopic dermatitis impacts the quality of life of families of children affected by AD. Methods A total of 3436 articles were identified via an online search of the MEDLINE health literature database and were screened for relevance to quality of life impacts on families with children affected by AD. Results Caring for children affected by AD can be an extremely time‐consuming task that can impair personal relationships, decrease psychosocial functioning, and cause sleep loss among family members of affected patients. Additionally, AD may result in work absence or decreased work productivity for caregivers. Special diets, irritant and allergen avoidance strategies, and alternative therapies are commonly used by patients to manage their disease and require large amounts of family involvement. Conclusions Atopic dermatitis can greatly decrease quality of life of families of affected children in various domains, including sleep, finances, and relationships. Early intervention and psychotherapy may be needed in some patients to address these quality of life impairments.

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Section: Methodsmentioning

confidence: 99%

“…On average, the annual cost of AD per patient in 1997 was $609 . In a recent study of families of children with moderate‐to‐severe AD, spending on AD averaged 34.8% of available salary . Therefore, managing AD can significantly impact family income and spending.…”

Section: Methodsmentioning

confidence: 99%

The impact of pediatric atopic dermatitis on families: A review

Yang

Beck

Sekhon

et al. 2018

Pediatric Dermatology

View full text Add to dashboard Cite

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“…The condition is characterized by physical symptoms such as itchy skin as well as psychosocial and mental burdens, adversely affecting children and their caregivers' quality of life . Atopic dermatitis also imposes significant economic burden for health care systems, attributable to factors such as physician visits and medications . Information on health‐related quality of life (HRQoL), combined with health care utilization data, can generate knowledge that identifies patients at risk of increased health care costs .…”

Section: Introductionmentioning

confidence: 99%

“…To assess HRQoL in clinical practice could therefore potentially function as an instrument for identifying children at high risk of accelerating health care costs . In addition, caregivers of children with AD are often affected by their child's condition, for example, by engaging in daily skin care routines; thus, the impact on caregivers' HRQoL could also impact health care utilization . Postulating that HRQoL measures to identify cost‐driving factors for children with AD and their caregivers generates pertinent information for physicians and policymakers to effectively target at‐risk children, better meet their health care needs, increase their HRQoL, and consequently reduce health care costs.…”

Section: Introductionmentioning

confidence: 99%

Associations between health‐related quality of life and health care costs among children with atopic dermatitis and their caregivers: A cross‐sectional study

Olsson

Bajpai

Yew

et al. 2019

Pediatric Dermatology

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Background/objectives Atopic dermatitis is associated with a decreased health‐related quality of life and contributes to substantial health care costs. It is important to understand what accelerates health care costs to inform various stakeholders, so they can effectively meet health care needs. This cross‐sectional study aims to explore associations between health‐related quality of life, health care costs, and cost‐accelerating variables. Methods Information on health‐related quality of life (HRQoL) was collected through generic and disease‐specific instruments from caregivers and children <16 years of age with a physician‐confirmed diagnosis of atopic dermatitis. The economic impact of atopic dermatitis was evaluated by analyzing information on health service utilization and other health care costs related to managing the condition. Results Children with high impact on health‐related quality of life presented an annual health care cost of US$ 3787 compared with US$ 2548 for moderately impacted and US$ 2258 among children for which the condition had low impact. The severity of atopic dermatitis, disease duration, and a lower health‐related quality of life was associated with greater health care costs. Analyses of subdomains of health‐related quality of life revealed correlations between “mood” and “personal relationships” on one hand and caregivers’ physical health and health care costs on the other hand. Conclusions Highly affected HRQoL is associated with increased health care costs and could be a valuable complement to traditional severity assessments. By using HRQoL instruments, burdens and symptoms beyond severity can be identified and addressed with interventions to increase HRQoL and subsequently reduce health care costs.

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“…Recent studies have documented that AD has a major emotional and financial impact on patients and their families thereby causing significant effects on quality of life [2•–4]. Behavioral difficulties, poor school performance and depression are also common [5].…”

Section: Introductionmentioning

confidence: 99%

Clinical implications of new mechanistic insights into atopic dermatitis

Leung

2016

Current Opinion in Pediatrics

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Purpose of review This review will examine recent advances in our understanding of atopic dermatitis (AD) and how these mechanisms provide a framework for new approaches to the management of this common skin disease. Recent findings The mechanisms by which epithelial skin barrier and immune responses contribute to the complex clinical phenotypes found in AD are being elucidated. AD often precedes food allergy because reduced skin barrier function allows environmental food allergens to penetrate the skin leading to systemic allergen sensitization. There is increasing evidence that AD is a systemic disease. New treatments are focused on intervention in polarized immune responses leading to allergic diseases. This includes antagonism of IL-4 and IL-13 effects. Prevention strategies involve maintaining normal skin barrier function with emollients to prevent allergens and microbes from penetrating the skin. Summary Recent work on the pathogenesis of AD has important implications for its clinical management including the development of effective barrier creams and biologicals targeting specific polarized immune pathways resulting in skin inflammation.

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The Financial and Emotional Impact of Atopic Dermatitis on Children and Their Families

Cited by 73 publications

References 30 publications

The impact of pediatric atopic dermatitis on families: A review

The impact of pediatric atopic dermatitis on families: A review

Associations between health‐related quality of life and health care costs among children with atopic dermatitis and their caregivers: A cross‐sectional study

Clinical implications of new mechanistic insights into atopic dermatitis

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