The fetal/placental weight ratio is associated with the incidence of atopic dermatitis in female infants during the first 14 months: The Hamamatsu Birth Cohort for Mothers and Children (HBC Study)

Matsumoto, Masako; Tsuchiya, Kenji J.; Yaguchi, Chizuko; Horikoshi, Yoshimasa; Furuta-Isomura, Naomi; Oda, Tomoaki; Kohmura-Kobayashi, Yukiko; Tamura, Naoaki; Uchida, Toshiyuki; Itoh, Hiroaki

doi:10.1016/j.ijwd.2020.02.009

Cited by 4 publications

(9 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Chronic chorioamnionitis was also found to be associated with asthma, 63 but HCA did not correlate with wheezing in term-born children. 55 Placental weight was not associated with the asthma predictive index or with AD, 62,68 but with the prescription of anti-asthma medication to infants up to 1 year of age after dichotomizing weight by 750 g 67 (Table 2).…”

Section: Results Of Synthesismentioning

confidence: 99%

“…However, some of the included studies did control for these covariates, and one study investigated the effects of air pollution 61 . Other limitations are the exclusion of combined fetal‐placental variables, such as the fetal‐to‐placental weight ratio, which might have been interesting to study, as this ratio was found to be associated with AD in girls 62 . The exclusion of publications prior to the year 2000 and the exclusion of research letters might have excluded some important findings.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Childhood atopic disorders in relation to placental changes—A systematic review and meta‐analysis

Bakoyan,

Cao,

Hansson

et al. 2024

Pediatric Allergy Immunology

View full text Add to dashboard Cite

Fetal programming may arise from prenatal exposure and increase the risk of diseases later in life, potentially mediated by the placenta. The objective of this systematic review was to summarize and critically evaluate publications describing associations between human placental changes and risk of atopic disorders during childhood. The review adhered to the Preferred Reporting Items for Systematic Reviews and Meta‐analysis guidelines. The inclusion criteria were original research articles or case reports written in English describing a human placental change in relation to disease occurring in offspring during childhood. The MEDLINE and EMBASE databases were searched for eligible studies. Risk of bias (RoB) was assessed using the ROBINS‐I tool. The results were pooled both in a narrative way and by a meta‐analysis. Nineteen studies were included (n = 12,997 participants). All studies had an overall serious RoB, and publication bias could not be completely ruled out. However, five studies showed that histological chorioamnionitis in preterm‐born children was associated with asthma‐related problems (pooled odds ratio = 3.25 (95% confidence interval = 2.22–4.75)). In term‐born children, a large placenta (≥750 g) increased the risk of being prescribed anti‐asthma medications during the first year of life. Placental histone acetylation, DNA methylation, and gene expression differences were found to be associated with different atopic disorders in term‐born children. There is some evidence supporting the idea that the placenta can mediate an increased risk of atopic disorders in children. However, further studies are needed to validate the findings, properly control for confounders, and examine potential mechanisms.

show abstract

Section: Results Of Synthesismentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Childhood atopic disorders in relation to placental changes—A systematic review and meta‐analysis

Bakoyan,

Cao,

Hansson

et al. 2024

Pediatric Allergy Immunology

View full text Add to dashboard Cite

show abstract

“…Of these, 1372 studies were deemed irrelevant and excluded (Figure 1), and 74 records were further reviewed using full texts. Finally, 32 studies with nearly 190,000 subjects were deemed eligible for inclusion in this meta‐analysis, 16–47 where one study compared two separate cohorts 47 (Table 1). Using the Newcastle–Ottawa Scale, 27 and 6 studies were considered as high and moderate quality, respectively.…”

Section: Resultsmentioning

confidence: 99%

“…There were 17 studies which evaluated the association between maternal active smoking during pregnancy and offspring eczema development, 16,17,20,[22][23][24][25][26][27][28][29]31,34,37,41,43,46 6 studies for food allergy 17,21,23,33,45,47 and 2 studies for food sensitisation. 17,18 There was no significant association between maternal active smoking during pregnancy and the risk of eczema development when all assessment types were considered (RR = 0.92; 95% CI 0.84-1.00; Figure 2).…”

Section: Maternal Active Smokingmentioning

confidence: 99%

Smoke exposure and childhood atopic eczema and food allergy: A systematic review and meta‐analysis

Lau,

Lee,

Yap

et al. 2023

Pediatric Allergy Immunology

View full text Add to dashboard Cite

BackgroundThere is no consensus on the effect of timing and type of smoke exposure on early allergy development. This study aimed to determine the relationship between early eczema or food allergy/hypersensitivity development in children by firstly investigating the effect of smoke exposure across critical development periods and secondly by analyzing effects of parental atcive or passive smoking.MethodsFour databases (PubMed, Web of Science, Scopus and Embase) were searched in May 2022 and assessed by two independent reviewers. Case–control, cross‐sectional or cohort studies reporting on smoke exposure from preconception to postnatal periods and atopic eczema, food allergy and/or hypersensitivity outcomes by age 3 years were included. The Newcastle–Ottawa Scale was used to assess study quality. Random effects model was used to estimate the pooled risk ratios.ResultsFrom 1689 identified records, 32 studies with nearly 190,000 subjects were included. Parental smoking during preconception, pregnancy and postnatal periods was generally not associated with the risk of eczema, food allergy and food sensitisation development by age 3 years. Maternal active smoking during pregnancy was negatively associated with self‐reported doctor diagnosis of eczema (RR = 0.87, 95% CI 0.77–0.98; I2 = 50.56) and maternal passive smoking during pregnancy was positively associated with clinician assessment of eczema in one study (RR = 1.38; 95% CI 1.06–1.79).ConclusionOur findings highlighted the importance of in utero programming in early‐life allergy development. Despite the weak evidence, our results suggest pregnant women should minimise their contact with second‐hand smoke to prevent offspring eczema development. There is a need for greater utilisation of objective allergy assessments in future studies.

show abstract

“…Khalief et al reported that placental size negatively correlated with mental health in children and adolescents 14 . We recently demonstrated that the fetal/placental weight ratio was associated with the incidence of atopic dermatitis in female infants 15 . Barker et al proposed the attractive concept of ‘Placental origins of chronic disease’ 16 .…”

Section: Introductionmentioning

confidence: 99%

Placental pathology predicts infantile neurodevelopment

Ueda

Tsuchiya

Yaguchi

et al. 2022

Sci Rep

Self Cite

View full text Add to dashboard Cite

The aim of present study was to investigate the association of placental pathological findings with infantile neurodevelopment during the early 40 months of life. 258 singleton infants were enrolled in the Hamamatsu Birth Cohort for Mothers and Children (HBC Study) whose placentas were saved in our pathological division. To assess the infantile neurodevelopment, we used Mullen Scales of Early Learning (gross motor, visual reception, fine motor, receptive language, expressive language) at 10, 14, 18, 24, 32, and 40 months. For obtaining placental blocks, we carried out random sampling and assessed eleven pathological findings using mixed modeling identified ‘Accelerated villous maturation’, ‘Maternal vascular malperfusion’, and ‘Delayed villous maturation’ as significant predictors of the relatively lower MSEL composite scores in the neurodevelopmental milestones by Mullen Scales of Early Learning. On the other hand, ‘Avascular villi’, ‘Thrombosis or Intramural fibrin deposition’, ‘Fetal vascular malperfusion’, and ‘Fetal inflammatory response’ were significant predictors of the relatively higher MSEL composite scores in the neurodevelopmental milestones by Mullen Scales of Early Learning. In conclusion, the present study is the first to report that some placental pathological findings are bidirectionally associated with the progression of infantile neurodevelopment during 10–40 months of age.

show abstract

The fetal/placental weight ratio is associated with the incidence of atopic dermatitis in female infants during the first 14 months: The Hamamatsu Birth Cohort for Mothers and Children (HBC Study)

Cited by 4 publications

References 46 publications

Childhood atopic disorders in relation to placental changes—A systematic review and meta‐analysis

Childhood atopic disorders in relation to placental changes—A systematic review and meta‐analysis

Smoke exposure and childhood atopic eczema and food allergy: A systematic review and meta‐analysis

Placental pathology predicts infantile neurodevelopment

Contact Info

Product

Resources

About

The fetal/placental weight ratio is associated with the incidence of atopic dermatitis in female infants during the first 14 months: The Hamamatsu Birth Cohort for Mothers and Children (HBC Study)

Cited by 4 publications

References 46 publications

Childhood atopic disorders in relation to placental changes—A systematic review and meta‐analysis

Childhood atopic disorders in relation to placental changes—A systematic review and meta‐analysis

Smoke exposure and childhood atopic eczema and food allergy: A systematic review and meta‐analysis

Placental pathology predicts infantile neurodevelopment

Contact Info

Product

Resources

About

The fetal/placental weight ratio is associated with the incidence of atopic dermatitis in female infants during the first 14 months: The Hamamatsu Birth Cohort for Mothers and Children (HBC Study)