2019
DOI: 10.1016/j.ajog.2019.06.013
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The fetal origins of mental illness

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Cited by 208 publications
(163 citation statements)
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References 214 publications
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“…The seasonal influenza vaccine has established efficacy in preventing maternal infection, as well as partially preventing the infant through passive immunity, and its administration remains best practice for protection of mother and child, with the World Health Organisation recognising pregnant women as a priority vulnerable group. In addition, educating pregnant women to contact their healthcare provide if they have a fever is recommended in order to expedite administration of antiviral medication and supportive care (228). Some authors consider the fact that influenza vaccination is not recommended in the first trimester in some countries as cause for concern, leaving women and the developing foetus vulnerable during a critical neurodevelopmental window (228).…”
Section: Discussionmentioning
confidence: 99%
“…The seasonal influenza vaccine has established efficacy in preventing maternal infection, as well as partially preventing the infant through passive immunity, and its administration remains best practice for protection of mother and child, with the World Health Organisation recognising pregnant women as a priority vulnerable group. In addition, educating pregnant women to contact their healthcare provide if they have a fever is recommended in order to expedite administration of antiviral medication and supportive care (228). Some authors consider the fact that influenza vaccination is not recommended in the first trimester in some countries as cause for concern, leaving women and the developing foetus vulnerable during a critical neurodevelopmental window (228).…”
Section: Discussionmentioning
confidence: 99%
“…[54][55][56] If the virus does cross the placental barrier, there is the worrying possibility that it will predispose to a range of adverse gestational outcomes, neurodevelopmental disorders, and, decades later, even schizophrenia. [57][58][59] The National Institute of Mental Health and Neurosciences, Bangalore, where I work, has launched a 24/7 toll-free national helpline to address mental health concerns related to COVID-19. On March 30, 2020, alone, about 2,500 calls were handled by a 90-member multidisciplinary team.…”
Section: Lockdown: the Health Care Crisismentioning
confidence: 99%
“…Neonatal development intimately depends on maternal health. Prior infections and disease states causing maternal in ammatory activation and cytokine storm have resulted in increased risk of autism spectrum disorder, schizophrenia, cerebral palsy, cognitive delay, depression, and bipolar disorder in exposed children [15][16][17]. The effect of the SARS-CoV-2 hyperin ammatory milieu on the developing fetus is yet to be seen.…”
Section: Ascertain the Impact Of Maternal Sars-cov-2 Infection On Fetmentioning
confidence: 99%