The features of intestinal tuberculosis by contrast-enhanced ultrasound

Yang, Gaoyi; Zhang, Wenzhi; Yu, Tong; Meng, Jun; Zhao, Di; Zhang, Xu; Xu, Jianping; He, Na

doi:10.1007/s11604-015-0459-5

Cited by 9 publications

(13 citation statements)

References 26 publications

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“…Generally, the CTE findings of ITB include: mural thickening, necrotic lymph nodes, ileocecal area involvement, fistulas and strictures. GIUS-related studies on ITB are rare [14, 34]. Common GIUS manifestations include: bowel wall thickening, bowel ulcers, hypoechoic bowel wall and abundant vascularity.…”

Section: Discussionmentioning

confidence: 99%

The potential role of CT enterography and gastrointestinal ultrasound in the evaluation of anti-tubercular therapy response of intestinal tuberculosis: a retrospective study

Zhu

et al. 2019

BMC Gastroenterol

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Background Accurate evaluation of anti-tubercular therapy (ATT) responses is crucial for both diagnosis and treatment of intestinal tuberculosis (ITB). Little is known about the role of cross-sectional imaging techniques in ITB follow-up assessment. We aimed to investigate the accuracy of cross-sectional imaging modalities, CT enterography (CTE) and gastrointestinal ultrasound (GIUS), in the evaluation of ATT responses in ITB patients. Methods Patients diagnosed with ITB and followed up by CTE and/or GIUS were retrospectively searched in the databases. Clinical, imaging, laboratory and endoscopic data were collected at baseline and the first follow-up visit. Responses were graded as good, partial and no response based on protocols described in the literature and by our institution. CTE evaluation was based on changes in the lesion area, mural thickness, enhancement patterns and lymph nodes, while GIUS evaluation was based on changes in bowel wall morphology and the Limberg score. Clinical evaluation was used as the gold-standard evaluation method, which was determined by a comprehensive impression of endoscopic changes along with symptomatic improvement and laboratory tests, with imaging results masked. Results Twenty patients with ITB were enrolled in our study. The first follow-up time was from 2 to 12 months (average 6 months). According to the gold standard evaluation, 11 patients were evaluated as having a good ATT response, while 9 had a partial response. A total of 18 patients were followed up by CTE, while 7 were followed up by GIUS, depending on medical and/or financial considerations. The accuracy of CTE and GIUS was 83% (15/18) and 85.7% (6/7), respectively. The sensitivity, specificity, PPV and NPV of CTE were 88.9, 77.8, 80 and 87.5%, respectively. Moreover, the sensitivity, specificity, PPV and NPV of GIUS were 100, 50, 83.3 and 100%, respectively. By combining the results of CTE and GIUS results, the overall accuracy was 90%, with sensitivity and specificity of 91.7 and 87.5%, respectively. Conclusion To our knowledge, this is the first study exploring the accuracy of the cross-sectional imaging modalities CTE/GIUS in the evaluation of ATT responses. Our results indicated their promising application prospect in clinical practice as a non-invasive and cost-effective approach. Electronic supplementary material The online version of this article (10.1186/s12876-019-1030-0) contains supplementary material, which is available to authorized users.

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Section: Discussionmentioning

confidence: 99%

The potential role of CT enterography and gastrointestinal ultrasound in the evaluation of anti-tubercular therapy response of intestinal tuberculosis: a retrospective study

Zhu

et al. 2019

BMC Gastroenterol

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“…In type 2, most patients had heterogeneous enhancement, and few had homogeneous enhancement. Heterogeneous enhancement correlated with caseous necrosis [36]. The arrival time for the contrast medium in the tuberculous intestine was 14.8 ± 1.3 s, and was therefore faster than in the healthy intestine [36].…”

Section: Gastrointestinal Tractmentioning

confidence: 92%

“…This also applies to macronodular changes in the peritoneum and mesentery [Figure 1c-h]. The smallest speck-like deposits are usually not visible on ultrasound [36]. With ascites, it may be possible to observe the adhesions [31,37].…”

Section: Peritoneummentioning

confidence: 99%

Section: Gastrointestinal Tractmentioning

confidence: 99%

“…Ileocecal region: The most frequent localization remains the ileocecal area (76-90%) [3,36,90]. The predilection in the ileocecal region is attributed to the high density of lymph follicles in this area [36]. In a study conducted by Barreiros et al, 100% of patients with intestinal tuberculosis presented intestinal wall thickening.…”

Section: Gastrointestinal Tractmentioning

confidence: 99%

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Comments and Illustrations of Ultrasound Findings in Extrapulmonary Tuberculosis Manifestations

Möller,

Löwe,

Jenssen

et al. 2024

Diagnostics

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This review describes the appearance of extrapulmonary tuberculosis manifestations in comprehensive and multiparametric ultrasound imaging. The aim is to increase awareness of typical ultrasound findings regarding extrapulmonary tuberculosis, correlate those with pathological features, and facilitate differential diagnosis. Point of care ultrasound protocols can be used as a screening method in high-risk populations, although the negative findings do not exclude tuberculosis. Conversely, the diagnosis of extrapulmonary tuberculosis can never be made using ultrasound alone, as many ultrasound findings in extrapulmonary tuberculosis are non-specific. However, ultrasound-based sampling techniques can significantly facilitate the collection of samples for microbiological or molecular proof of tuberculosis, as well as facilitating the establishment of alternative diagnoses.

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Imaging of Gastrointestinal Tuberculosis

Prabhakar

Kalra

2022

Imaging of Tuberculosis

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The features of intestinal tuberculosis by contrast-enhanced ultrasound

Abstract: CEUS found detailed patterns of bowel wall enhancement of intestinal tuberculosis and had the potential to provide useful information for the diagnosis of suspected patients.

Cited by 9 publications

References 26 publications

The potential role of CT enterography and gastrointestinal ultrasound in the evaluation of anti-tubercular therapy response of intestinal tuberculosis: a retrospective study

The potential role of CT enterography and gastrointestinal ultrasound in the evaluation of anti-tubercular therapy response of intestinal tuberculosis: a retrospective study

Comments and Illustrations of Ultrasound Findings in Extrapulmonary Tuberculosis Manifestations

Imaging of Gastrointestinal Tuberculosis

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