The feasibility of wireless capsule endoscopy in detecting small intestinal pathology in children under the age of 8 years: a multicentre European study

Fritscher-Ravens, Annette; Scherbakov, Peter; Bufler, Philip; Torroni, F.; Ruuska, Tarja; Nuutinen, Hannu; Thomson, Mary; Tabbers, Merit M.; Milla, Peter J.

doi:10.1136/gut.2009.177774

Cited by 117 publications

(104 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In children, the ability and willingness to swallow endoscopic capsules can be influenced by the child's age and cognitive understanding, personality, acceptance by parents, and skill of the investigator in turning the ingestion into an interactive game 3. However, even in adolescents, up to one‐third of patients describe difficulties swallowing standard size tablets 4.…”

Section: Discussionmentioning

confidence: 99%

Comparing swallowing of capsule to endoscopic placement of capsule endoscopy in children

et al. 2017

View full text Add to dashboard Cite

Background and AimCapsule endoscopy (CE) offers a method of directly visualizing areas of the small bowel not accessible by conventional endoscopy. Some children are unable to swallow the capsule requiring endoscopic placement under general anesthesia. The aim of the present study was to identify any differences between children requiring endoscopic placement and those able to swallow the capsule.MethodsRetrospective chart review of consecutive CE in a tertiary pediatric center was conducted. Patient demographics, outcomes, and complications between the two groups were noted. Paired t‐test comparing continuous variables and Fisher exact test for categorical data were used.ResultsA total of 104 CEs were performed in 88 patients, median age 12.8 (range: 1.6–18.5) years. Almost half, 49% (51/104), swallowed the capsule. Children requiring endoscopic placement were significantly younger (9.8 vs 14.2 years; P < 0.001), lighter (34.5 vs 54.9 kg; P < 0.0001), and had longer small intestinal transit time (308 vs 229 min; P < 0.0001). Positive findings were more likely in those who swallowed the capsule (50% vs 30%, P = 0.017), likely a reflection of the indications for procedure. Poor views were found in 30% (16/53) of patients in the endoscopic placement group due to iatrogenic bleeding from biopsies taken from concurrent procedures but did not affect outcome or subsequent patient management.ConclusionsCE is safe and well tolerated in children. Children requiring endoscopic placement were significantly younger, lighter, had longer small intestine transit time, and less likely to have positive findings. Concurrent biopsies during capsule placement increase the likelihood of inadequate views but did not affect outcome or management.

show abstract

Section: Discussionmentioning

confidence: 99%

Comparing swallowing of capsule to endoscopic placement of capsule endoscopy in children

et al. 2017

View full text Add to dashboard Cite

show abstract

“…On the other hand, it is still controversial to use CE for the children under 10 years of age. Several studies described that CE has high diagnostic yield to those patients under 10 years of age (de'Angelis, 2007;Atay, 2009;Fritscher-Ravens, 2009;, and their small body size don't relate to the risk of capsule retention, which is the most serious complication in this modality as described in the latter paragraph. In addition, there was no difference in the gastric and small intestinal passage time between adult and pediatric patients .…”

Section: Agementioning

confidence: 98%

“…In addition, there was no difference in the gastric and small intestinal passage time between adult and pediatric patients . In young children (1.5-8 yr), a previous study reported CE detected small intestinal pathology in 45% (37 of 83 patients) in whom their indications are gastrointestinal bleeding, suspected Crohn's disease, abnormal pain, protein loss and malabsorption (Fritscher-Ravens, 2009). Because of no incidence of retention among those aged patients (1.5-7.9yr), CE is considered as feasible and safe down to the age of 1.5 yr. As another important aspect, swallowing of CE is unavoidable problem in small children.…”

Section: Agementioning

confidence: 98%

“…Transit time of CE and analyzed pathway by the software will help to assess the localization of detected abnormality in the small intestine. In pediatric patients with suspected small intestinal disease, CE detect abnormal findings in 55% (286/523) of cases (Tokuhara, 2010;de'Angelis, 2007;Atay, 2009;Fritscher-Ravens, 2009;Moy, 2009;Guilhon de Araujo Sant'Anna, 2005;Thomson, 2010;Argüelles-Arias, 2004;Pinho, 2008;Stiffler, 2003). Based on the detected abnormalities by CE in addition to the clinical and/or other laboratory informations, various small intestinal diseases are diagnosed or suggested, or further elucidated of their involvements of small intestinal lesions in known diseases (Table 1).…”

Section: Abnormalities Assessed By Cementioning

confidence: 99%

See 1 more Smart Citation

Wireless Capsule Endoscopy in Pediatric Gastrointestinal Diseases

Tokuhara¹

2011

New Techniques in Gastrointestinal Endoscopy

View full text Add to dashboard Cite

“…an endoscopic placement of the capsule was 1.5 years old [13][14][15]. It was reported that the endoscopic replacement into the stomach with polyp snare was performed in a 42-month-old girl in Korea [16].…”

Section: The Procedures Of Cementioning

confidence: 99%

The Role of Capsule Endoscopy in the Diagnosis of Crohn's Disease

Rhee

2012

Pediatr Gastroenterol Hepatol Nutr

View full text Add to dashboard Cite

The examination of small bowel in Crohn's disease (CD) is very important. Capsule endoscopy (CE) has been recognized as a good tool for evaluation of small bowel. The capsule placement is achieved endoscopically for Children not to swallow capsule. CE is superior to any other modalities for examination of small-bowel. The large portion of pediatric patients with known CD were found with CE to have more extensive and newly diagnostic small-bowel disease. All of them had therapeutic changes. The most side effect of CE is capsule retention. The capsule retention rate in pediatric CD is about 7.3%. The patency capsule helps to predict the possibility of capsule retention. For the improving of the diagnostic accuracy, the experience of more than 20 readings of CE is needed. (Pediatr Gastroenterol Hepatol Nutr 2012; 15: 8∼12)

show abstract

The feasibility of wireless capsule endoscopy in detecting small intestinal pathology in children under the age of 8 years: a multicentre European study

Abstract: Objective: To systematically evaluate the feasibility and methodology to carry out wireless capsule endoscopy (WCE) in children ,8 years to define small intestinal pathology.

Cited by 117 publications

References 37 publications

Comparing swallowing of capsule to endoscopic placement of capsule endoscopy in children

Comparing swallowing of capsule to endoscopic placement of capsule endoscopy in children

Wireless Capsule Endoscopy in Pediatric Gastrointestinal Diseases

The Role of Capsule Endoscopy in the Diagnosis of Crohn's Disease

Contact Info

Product

Resources

About