The fate of the failing Fontan circulation—No two are alike

Puri, Kriti; Schweiger, Martin; Rossano, Joseph W.

doi:10.1016/j.healun.2021.08.014

Cited by 1 publication

(1 citation statement)

References 15 publications

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“…The main challenge with UNOS data is the high number of missing values, requiring variable elimination and complex data imputation methods (5)(6)(7). The ISHLT registry, on the other hand, includes the UNOS database plus data from other centers worldwide -recently over 350 entities contributing (8). The ISHLT registry does not include wait list duration or mortality (9,10).…”

Section: Post Heart Transplant Outcome Predictionmentioning

confidence: 99%

Artificial intelligence guidance of advanced heart failure therapies: A systematic scoping review

Al‐Ani

Chen

Hashky

et al. 2023

Front. Cardiovasc. Med.

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IntroductionArtificial intelligence can recognize complex patterns in large datasets. It is a promising technology to advance heart failure practice, as many decisions rely on expert opinions in the absence of high-quality data-driven evidence.MethodsWe searched Embase, Web of Science, and PubMed databases for articles containing “artificial intelligence,” “machine learning,” or “deep learning” and any of the phrases “heart transplantation,” “ventricular assist device,” or “cardiogenic shock” from inception until August 2022. We only included original research addressing post heart transplantation (HTx) or mechanical circulatory support (MCS) clinical care. Review and data extraction were performed in accordance with PRISMA-Scr guidelines.ResultsOf 584 unique publications detected, 31 met the inclusion criteria. The majority focused on outcome prediction post HTx (n = 13) and post durable MCS (n = 7), as well as post HTx and MCS management (n = 7, n = 3, respectively). One study addressed temporary mechanical circulatory support. Most studies advocated for rapid integration of AI into clinical practice, acknowledging potential improvements in management guidance and reliability of outcomes prediction. There was a notable paucity of external data validation and integration of multiple data modalities.ConclusionOur review showed mounting innovation in AI application in management of MCS and HTx, with the largest evidence showing improved mortality outcome prediction.

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