The failed gastrointestinal anastomosis: an inevitable catastrophe?

Pickleman, Jack; Watson, William L.; Cunningham, John J.; Fisher, Susan G.; Gamelli, Richard L.

doi:10.1016/s1072-7515(99)00028-9

Cited by 129 publications

(95 citation statements)

References 35 publications

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“…198 In general, anastomotic leak of the gastrointestinal tract is associated with increased mortality, increased morbidity and prolonged hospital stay, and can impact on the long-term functional outcome of patients. In 1999, Pickleman and co-workers 13 stated that it was one of the most feared complications of gastrointestinal surgery.…”

Section: Discussionmentioning

confidence: 99%

“…It is associated with increased morbidity and mortality and prolonged hospital length of stay, and can also impact upon long-term outcome. 13 Anastomotic leak is an uncommon event and was not ranked among the complications at time of hospital discharge from the national sources, although it is possible that the generic complication 'gastrointestinal complication' after 'excision of rectum' (Office of Population Censuses and Surveys (OPCS) 4 code H33) might include leak. Anastomotic leak was selected as it had been consistently identified by the SASM as a cause of significant mortality, with the risk of fatality from anastomotic leak associated with a delay in recognition, detection and investigation.…”

Section: Rationale For Inclusion Of Anastomotic Leakmentioning

confidence: 99%

See 1 more Smart Citation

The measurement and monitoring of surgical adverse events

Bruce

Russell

Mollison

et al. 2001

Health Technol Assess

296

209

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Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per monograph and for the rest of the world £3 per monograph.You can order HTA monographs from our Despatch Agents:-fax (with credit card or official purchase order) -post (with credit card or official purchase order or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you either to pay securely by credit card or to print out your order and then post or fax it. Contact Payment methods Paying by chequeIf you pay by cheque, the cheque must be in pounds sterling, made payable to Direct Mail Works Ltd and drawn on a bank with a UK address. Paying by credit cardThe following cards are accepted by phone, fax, post or via the website ordering pages: Delta, Eurocard, Mastercard, Solo, Switch and Visa. We advise against sending credit card details in a plain email. Paying by official purchase orderYou can post or fax these, but they must be from public bodies (i.e. NHS or universities) within the UK.We cannot at present accept purchase orders from commercial companies or from outside the UK. How do I get a copy of HTA on CD?Please use the form on the HTA website (www.hta.ac.uk/htacd.htm). Or contact Direct Mail Works (see contact details above) by email, post, fax or phone. HTA on CD is currently free of charge worldwide.The website also provides information about the HTA Programme and lists the membership of the various committees. HTAThe measurement and monitoring of surgical adverse events NHS R&D HTA ProgrammeT he NHS R&D Health Technology Assessment (HTA) Programme was set up in 1993 to ensure that high-quality research information on the costs, effectiveness and broader impact of health technologies is produced in the most efficient way for those who use, manage and provide care in the NHS.Initially, six HTA panels (pharmaceuticals, acute sector, primary and community care, diagnostics and imaging, population screening, methodology) helped to set the research priorities for the HTA Programme. However, during the past few years there have been a number of changes in and around NHS R&D, such as the establishment of the National Institute for Clinical Excellence (NICE) and the creation of three new research programmes: Service Delivery and Organisation (SDO); New and Emerging Applications of Technology (NEAT); and the Methodology Programme.Although the National Coordinating Centre for Health Technology Assessment (NCCHTA) commissions research on behalf of the Methodology Programme, it is the Methodology Group that now considers and advises the Methodology Programme Director on the best research projects to pursue.The research reported in this monograph was funded as project number 97/16/04.The views expressed in this publication are those of the authors and not necessarily those of the Methodology Programme, HTA Programme or the Department of Health. The editors wish to emphasise that funding and publication of this research by the NHS should not be taken as implicit supp...

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Section: Discussionmentioning

confidence: 99%

Section: Rationale For Inclusion Of Anastomotic Leakmentioning

confidence: 99%

The measurement and monitoring of surgical adverse events

Bruce

Russell

Mollison

et al. 2001

Health Technol Assess

296

209

View full text Add to dashboard Cite

show abstract

“…A deiscência anastomótica, após cirurgias colorretais, se constitui num evento extremamente de-vastador, não só pelo seu profundo impacto negativo sobre os resultados clínicos demonstrados pelo aumento na morbidade e nas taxas de mortalidade em até 7x 6,13,24,25 , como também pelo pior prognóstico após cirurgias para câncer, com aumento nas taxas de recorrência local 26 , diminuição nas sobrevidas global de 5 anos e câncer específica 27 . Além destes fatores anteriormente considerados, o vazamento de uma anastomose intestinal, requer, na maioria das vezes, uma reintervenção cirúrgica com ressecção do local da anastomose e confecção de estomias, que, quando realizadas sobre o cólon, implica na manutenção permanente da mesma em até 60% dos casos 5,28,29 .…”

Section: Discussionunclassified

Influência da cola Bioglue® na deiscência de anastomose colônica: estudo experimental

Lucena

Mathias

Filho

et al. 2007

Rev bras. colo-proctol.

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RESUMO: A grande parte da morbimortalidade associada com a cirurgia colorretal, é associada com a deiscência anastomótica. Trabalhos experimentais sobre a utilidade de adesivos tissulares nas anastomoses colônicas são controversos, assim como estudos clínicos prospectivos randomizados são ausentes. O adesivo cirúrgico BioGlue    , formado por dois componentes -albumina sérica bovina purificada e glutaraldeído, forma uma ligação co-valente entre esses dois componentes e as proteínas teciduais no local de aplicação. O objetivo do estudo é avaliar a eficácia da BioGlue     na prevenção da deiscência anastomótica colônica em ratos. Foram utilizados 30 ratos machos da raça Wistar albino. A anastomose colocolônica foi confeccionada com sutura em pontos separados com polipropileno 5-0 (grupo 1) e aplicação da cola BioGlue     envolvendo a anastomose (grupo 2). Avaliaram-se a formação e extensão das aderências, a pressão de ruptura nas anastomoses e as alterações histológicas. Apenas um animal do grupo 1 (7%) faleceu, sendo constatada na necropsia, obstrução intestinal com grande distensão de alças. A mortalidade no grupo 2, por outro lado, foi de 10 animais (67%), sendo observado: distensão de alças intestinais, vazamento anastomótico e, em algumas situações, franca peritonite fecal por deiscência quase que total da anastomose. O presente trabalho nos permitiu concluir que, o uso da Bioglue® nas anastomoses colônicas realizadas em ratos, promoveu um aumento na morbimortalidade que foi estatisticamente significante comparado à sutura convencional.

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“…A variety of techniques are used, including suturing, stapling, tissue fusion and compression rings [1]. Despite continuing advances, leakage remains a potentially devastating complication, with a high (6-22%) mortality following surgery [2]. The cause is poor blood supply (ischemia), aggravated by mechanical tension and tissue damage from radiation therapy [3].…”

Section: Introductionmentioning

confidence: 99%

Surgical wound monitoring by MRI with a metamaterial-based implanted local coil

et al. 2018

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Abstract. An implantable sensor for monitoring surgical wounds after bowel reconstruction is proposed. The sensor consists of a coupled pair of 8-element magneto-inductive ring resonators, designed for mounting on a biofragmentable anastomosis ring to give a local increase in signal-to-noise ratio near an annular wound during 1 H magnetic resonance imaging. Operation on an anti-symmetric spatial mode is used to avoid coupling to the B 1 field during excitation, and a single wired connection is used for MRI signal output. The electrical response and field-of-view are estimated theoretically. Prototypes are constructed from flexible elements designed for operation at 1.5 T, electrical responses are characterized and local SNR enhancement is confirmed using agar gel phantoms.

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The failed gastrointestinal anastomosis: an inevitable catastrophe?

Cited by 129 publications

References 35 publications

The measurement and monitoring of surgical adverse events

The measurement and monitoring of surgical adverse events

Influência da cola Bioglue® na deiscência de anastomose colônica: estudo experimental

Surgical wound monitoring by MRI with a metamaterial-based implanted local coil

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