The factors correlated with COVID-19 vaccination coverage in Chinese hypertensive patients managed by community general practitioner

Abstract

This study aims to describe COVID-19 vaccination coverage and its influential factors in hypertensive patients who were administered by community general practitioners in China. A cross-sectional survey was carried out using data from electronic health record systems. The subjects were hypertensive patients who had been involved in the health management of the Essential Public Health Service (EPHS) program in Hangzhou City, China. As of Aug 3, 2022, the full and booster vaccination rates were 77.53% and 60.97% in randomly selected 96,498 subjects. There were disparities across regions, age, and gender in the distribution of COVID-19 vaccination coverage. Obesity and daily alcohol consumption were factors in the promotion of COVID-19 vaccination. Current smoking, non-daily physical exercise, irregular medication adherence, and comorbidities were risk factors for COVID-19 vaccination. Coverage rates have decreased depending on the number of risk factors. The ORs (95% CI) were 1.78 (1.61 ~ 1.96) of full vaccination and 1.74 (1.59 ~ 1.89) of booster vaccination in subjects with ≥4 risk factors, compared to those without risk factors. In summary, the progress of COVID-19 vaccination among community hypertensive patients lagged behind that of the general population during the same period. Individuals who lived in urban areas, were elderly, and had an irregular medication adherence, comorbidities, and multiple risk factors should be highlighted in the COVID-19 vaccination campaign.

Heterologous Booster with BNT162b2 Induced High Specific Antibody Levels in CoronaVac Vaccinees

“…Although the presence of comorbidities may hinder the induction of immune responses by different vaccines [ 53 , 57 , 58 ], in our study, we did not observe statistical differences between anti-RBD IgG and IgA antibody levels and the presence of comorbidities. In contrast, individuals with no comorbidities, vaccinated with BNT162b2, presented higher anti-spike IgG levels.…”

Impact of epidemic prevention policies on public vaccination willingness: empirical research in China

“…In the United States and Italy, for example, parents who do not comply with childhood vaccination schedules are barred from enrolling their children in public schools and daycare centers, and in some cases are required to pay penalties ( 10 ). Smoking, non-daily physical exercise, irregular medication adherence, and comorbidities were found to be risk factors for COVID-19 vaccination among Chinese adults ( 11 ). On July 20, 2023, the coverage rate of the first dose of the COVID-19 vaccine was 92.9% and the full vaccination rate was 90.5% among the whole population in mainland China ( 12 ).…”