The Factors Affecting Recurrence of Symptoms after Infrainguinal Arterial Endovascular Angioplasty

Bae, Mi Ju; Lee, Jong Geun; Chung, Sung Woon; Lee, Chung Won; Kim, Chang Won

doi:10.5090/kjtcs.2014.47.6.517

Cited by 5 publications

(4 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, many patients are poor candidates for these interventions due to their comorbidities such as diabetes despite the availability of treatment options [ 7 ]. Moreover, 20% of treated patients develop recurrent symptoms that cannot further undergo vascular intervention [ 8 , 9 ]. Thus, the induction of endogenous revascularization has been attempted to establish an alternative strategy of revascularization that ensures efficient re-establishment of blood flow to ischemic tissues and improve PAD patients’ clinical outcomes.…”

mentioning

confidence: 99%

Role of Vascular Smooth Muscle Cell Phenotype Switching in Arteriogenesis

Ashraf

Zen

2021

IJMS

View full text Add to dashboard Cite

Arteriogenesis is one of the primary physiological means by which the circulatory collateral system restores blood flow after significant arterial occlusion in peripheral arterial disease patients. Vascular smooth muscle cells (VSMCs) are the predominant cell type in collateral arteries and respond to altered blood flow and inflammatory conditions after an arterial occlusion by switching their phenotype between quiescent contractile and proliferative synthetic states. Maintaining the contractile state of VSMC is required for collateral vascular function to regulate blood vessel tone and blood flow during arteriogenesis, whereas synthetic SMCs are crucial in the growth and remodeling of the collateral media layer to establish more stable conduit arteries. Timely VSMC phenotype switching requires a set of coordinated actions of molecular and cellular mediators to result in an expansive remodeling of collaterals that restores the blood flow effectively into downstream ischemic tissues. This review overviews the role of VSMC phenotypic switching in the physiological arteriogenesis process and how the VSMC phenotype is affected by the primary triggers of arteriogenesis such as blood flow hemodynamic forces and inflammation. Better understanding the role of VSMC phenotype switching during arteriogenesis can identify novel therapeutic strategies to enhance revascularization in peripheral arterial disease.

show abstract

mentioning

confidence: 99%

Role of Vascular Smooth Muscle Cell Phenotype Switching in Arteriogenesis

Ashraf

Zen

2021

IJMS

View full text Add to dashboard Cite

show abstract

“…In the study by Bae et al . [ 20 ], the presence of a dorsal arch (HR = 0.66, p = 0.047) and dyslipidemia (HR = 5.81, p = = 0.031) were significant factors affecting the recurrence of symptoms after endovascular treatment of occlusive femoro-popliteal lesions. Moreover, other studies have shown the importance of BTK outflow quality for the patency of stents implanted into femoro- popliteal vascular segments [ 1 , 21 ].…”

Section: Discussionmentioning

confidence: 99%

The association between periprocedural factors and the late outcome of percutaneous stenting of lower extremity arteries. A retrospective cohort study

Grzelązka¹,

Koza²,

Trofimiuk³

et al. 2015

pwki

View full text Add to dashboard Cite

IntroductionAbout 20–30% of the population have peripheral artery disease. Many of them require intervention, with a percutaneous procedure currently being the first choice. However, the outcomes of these interventions need regular evaluation due to continuous progress in endovascular techniques and the devices used.AimThe aim of this study was to analyze procedural factors influencing the outcome of endovascular intervention in patients stented for the first time due to lower extremity atherosclerosis.Material and methodsThe medical documentation of 91 patients with at least 1 year of follow-up after stenting of a lower limb artery was retrospectively evaluated. Uni- and multivariate analyses were performed.ResultsThe mean observation time was 544.4 ±502.9 days. The primary patency of a stent after such a follow-up was 68.1%. Cox proportional hazard analysis revealed that the risk of target lesion revascularization was affected by the following (hazard risk, 95% confidence interval): the number of vascular segments with significant lesions (13.14, 2.28–75.8); critical limb ischemia (5.68, 1.23–26.2); localization of the target lesion in an aorto-iliac in comparison with a femoro-popliteal vascular segment (0.37, 0.14–0.7); aorto-iliac lesion class according to the TASC-II consensus (1.96, 1.1–3.8); and claudication distance (1.02, 1.01–1.03).ConclusionsThe common primary patency of a stent implanted into either an aorto-iliac or a femoro-popliteal vascular segment was similar to that found in other reports. The main factors affecting the outcome of the endovascular procedures performed were mainly related to atherosclerosis severity, not to the type of technique or device used.

show abstract

“…Visto que a DAOP dos MMII é um problema de saúde pública crescente, com altos custos para o paciente e para o sistema de saúde, é necessário pesquisar exames menos invasivos e de baixo custo que possam ajudar na decisão terapêutica mais adequada para seus portadores. Sugerindo inclusive, qual artéria deveria ser revascularizada [6][7][8][9][10][11][12][13][14][15][16][17][18] .…”

Section: Introductionunclassified

Correlação entre o índice de resistência vascular e a arteriografia na avaliação do leito arterial distal na isquemia crítica dos membros inferiores

Buril,

Lins,

Silva

et al. 2024

J. vasc. bras.

View full text Add to dashboard Cite

Resumo Contexto Pacientes com isquemia crítica (IC) dos membros inferiores (MMII) precisam de arteriografia para o planejamento da cirurgia de revascularização. A ultrassonografia Doppler (UD) não é invasiva e, através da aferição do índice de resistência (IR), pode fornecer informações sobre as artérias distais. Objetivos Correlacionar a Classificação Angiográfica de Rutherford com o IR na avaliação do leito arterial distal dos MMII. Métodos Estudo transversal, realizado em hospital público terciário, com 120 pacientes portadores de IC dos MMII, entre setembro de 2019 a abril de 2022. Foi comparado o IR das artérias da perna passíveis de serem receptoras de revascularização com a imagem obtida através da arteriografia dessas artérias em acordo com a Classificação Angiográfica de leito distal de Rutherford. Resultados Foram avaliados 120 MMII em 120 pacientes com idade média de 68,6 anos. A amostra foi composta de 50,0% de pacientes do sexo masculino. Na amostra, 90,0% pacientes encontravam-se na classe cinco de Rutherford. Os valores do IR encontrados para as artérias de perna apresentaram uma correlação positiva, estatisticamente significativa, quando comparados com a Classificação de Rutherford (tibial anterior, p< 0,01; tibial posterior, p = 0,012 e fibular, p = 0,034 e artéria dorsal do pé, p < 0,001). Conclusões Neste estudo, os IRs das artérias da perna obtidos através da ultrassonografia Doppler apresentaram uma correlação positiva quando comparados à classificação de Rutherford. Em pacientes com isquemia crítica, esse índice pode ser útil na avaliação do leito arterial distal dos membros inferiores.

show abstract

The Factors Affecting Recurrence of Symptoms after Infrainguinal Arterial Endovascular Angioplasty

Cited by 5 publications

References 14 publications

Role of Vascular Smooth Muscle Cell Phenotype Switching in Arteriogenesis

Role of Vascular Smooth Muscle Cell Phenotype Switching in Arteriogenesis

The association between periprocedural factors and the late outcome of percutaneous stenting of lower extremity arteries. A retrospective cohort study

Correlação entre o índice de resistência vascular e a arteriografia na avaliação do leito arterial distal na isquemia crítica dos membros inferiores

Contact Info

Product

Resources

About