The fabrication and characterization of bioactive Akermanite/Octacalcium phosphate glass-ceramic scaffolds produced via PDC method

Abdollahi, Sorosh; Paryab, Amirhosein; Khalilifard, Rashid; Anousheh, Mohsen; Khachatourian, Adrine Malek

doi:10.1016/j.ceramint.2020.11.003

Cited by 8 publications

(5 citation statements)

References 41 publications

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“…The exchange between H + ions in the SBF solution and cations in the HaP and HMT composite samples has increased the pH of the SBF solution. The proposed exchange mechanism of Kocubo can explain the release of cations and the increase in pH to form a HaP layer on the surface [ 37 , 38 ]. According to the results shown in Fig.…”

Section: Resultsmentioning

confidence: 99%

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Enhanced mechanical properties and biocompatibility of hydroxyapatite scaffolds by magnesium and titanium oxides for bone tissue applications

Arab,

Behboodi,

Malek Khachatourian

et al. 2024

Heliyon

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Section: Resultsmentioning

confidence: 99%

“…Several scaffold fabrication techniques include sol-gel, gel-casting, connection/network, phase separation, extrusion, injection molding, 3D printing, freeze drying, and polymer-derived ceramic method [ [34] , [35] , [36] , [37] , [38] ]. Among these methods, gel-casting is a promising technique for fabricating porous ceramics.…”

Section: Introductionmentioning

confidence: 99%

Enhanced mechanical properties and biocompatibility of hydroxyapatite scaffolds by magnesium and titanium oxides for bone tissue applications

Arab,

Behboodi,

Malek Khachatourian

et al. 2024

Heliyon

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“…For example, with only 5 g of preceramic polymer, 3 g of silica particles could yield. The PDC method is a novel approach for the fabrication of ceramic bodies through pyrolysis of a polymer via heat treatment in the air [17][18][19] or inert atmosphere. 20,21 Active or non-active fillers are usually added to the polymer to tailor the composition and properties.…”

Section: Introductionmentioning

confidence: 99%

Large scale synthesis of mesoporous and nonporous silica submicron particles via polymer‐derived ceramic method

Paryab,

Saghatchi,

Behsam

et al. 2023

Int J Applied Ceramic Tech

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Mesoporous silica particles (MSPs) are highly important in applications like H2 storage, catalysis/biocatalysis, adsorption, separation, and particularly in biomedical applications. The typical methods for producing MSPs are fast self‐assembly, soft and hard templating, and the modified Stöber method. These approaches have drawbacks like high cost, being time‐consuming, and low scale. Herein, as a novel strategy, a polymer‐derived ceramic method for large‐scale production of mesoporous and dense silica submicron particles with high yield and low cost is presented. This method requires commercial silicone resin, polydimethylsiloxane, as the main precursor of silica. However, this technique did not show high control over the size and surface area compared with the typical methods of MSPs synthesis but is definitely a significant step toward the large‐scale synthesis of MSPs.

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“…Considering all the above, it is easy to acknowledge ternary silicate bioceramics, such as diopside (D), akermanite (A), or merwinite (M), as frequently used materials in bone regeneration applications. Numerous studies previously investigated their properties, including the capacity to inhibit microbial growth, which is particularly critical for bone matrix [ 9 , 16 , 17 ], and concluded their applicability for TE as pure structures [ 6 , 10 , 18 , 19 , 20 ], or doped for improved bioactivity [ 21 , 22 , 23 , 24 ]. Calcium magnesium silicates have been produced in the form of particles (subsequently employed as fillers or decorations), thin or thick coatings, as well as porous scaffolds; most researchers have reported suitable mechanical properties, high bioactivity, and lack of cytotoxicity.…”

Section: Introductionmentioning

confidence: 99%

Composite Fibers Based on Polycaprolactone and Calcium Magnesium Silicate Powders for Tissue Engineering Applications

et al. 2022

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The present work reports the synthesis and characterization of polycaprolactone fibers loaded with particulate calcium magnesium silicates, to form composite materials with bioresorbable and bioactive properties. The inorganic powders were achieved through a sol–gel method, starting from the compositions of diopside, akermanite, and merwinite, three mineral phases with suitable features for the field of hard tissue engineering. The fibrous composites were fabricated by electrospinning polymeric solutions with a content of 16% polycaprolactone and 5 or 10% inorganic powder. The physico-chemical evaluation from compositional and morphological points of view was followed by the biological assessment of powder bioactivity and scaffold biocompatibility. SEM investigation highlighted a significant reduction in fiber diameter, from around 3 μm to less than 100 nm after the loading stage, while EDX and FTIR spectra confirmed the existence of embedded mineral entities. The silicate phases were found be highly bioactive after 4 weeks of immersion in SBF, enriching the potential of the polymeric host that provides only biocompatibility and bioresorbability. Moreover, the cellular tests indicated a slight decrease in cell viability over the short-term, a compromise that can be accepted if the overall benefits of such multifunctional composites are considered.

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The fabrication and characterization of bioactive Akermanite/Octacalcium phosphate glass-ceramic scaffolds produced via PDC method

Cited by 8 publications

References 41 publications

Enhanced mechanical properties and biocompatibility of hydroxyapatite scaffolds by magnesium and titanium oxides for bone tissue applications

Enhanced mechanical properties and biocompatibility of hydroxyapatite scaffolds by magnesium and titanium oxides for bone tissue applications

Large scale synthesis of mesoporous and nonporous silica submicron particles via polymer‐derived ceramic method

Composite Fibers Based on Polycaprolactone and Calcium Magnesium Silicate Powders for Tissue Engineering Applications

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