The extracts ofAngelica sinensisinhibit lipid oxidation in fish erythrocytes and improve growth, digestive, absorptive and antioxidant capacity in juvenile Jian carp (Cyprinus carpiovar. Jian)

Abstract

The study explored the effects of ethyl ether extract, ethyl acetate extract (EAE), acetone extract, ethanol extract and aqueous extract of Angelica sinensis (EAs) and ethoxyquin (EQ) on lipid oxidation in erythrocytes and growth, digestive, absorptive and antioxidant capacity in carp (Cyprinus carpio var. Jian). The results indicated that EAs and EQ respectively at the concentrations of 0.5 and 0.25 mg/ml suppressed lipid oxidation by decreasing the generation of ROS and restoring the activities of antioxidants in hydroxyl radical-treated erythrocytes. Of all of the examined EAs, EAE showed the strongest protective effects against lipid oxidation in carp erythrocytes. The antioxidant effects of EQ at the concentration of 0.25 mg/ml were stronger than that of EAE at the concentration of 0.5 mg/ml in fish erythrocytes. The antioxidative activities of EAs in carp erythrocytes were positively correlated with their phenols content. Moreover, dietary EAE raised growth performance in fish. The appropriate concentration of EAE for the growth of fish was estimated to be 3.544 g/ kg diet. Dietary EAE increased digestive and absorptive capacity in carp and improved antioxidant capacity in copper-treated carp. So, EAE could be used as a potential natural antioxidant and inhibitor of copper stress in fish.

Model systems for studying lipid oxidation associated with muscle foods: Methods, challenges, and prospects

“…There are additional examples of erythrocyte models to study effects of antioxidants, feed ingredients on lipid oxidation in muscles. Hua-Tao et al (2019) investigated effects of extract of Angelica sinensis and ethoxyquin on lipid oxidation in erythrocytes and on growth, digestion, and absorptive and antioxidant capacity in carp muscle. The results indicated that Angelica sinensis extracts and ethoxyquin at concentrations of 0.5 and 0.25 mg/ml suppressed lipid oxidation by decreasing the generation of reactive oxygen species and restoring the activities of antioxidants in hydroxyl radical-treated erythrocytes.…”

The role of currently used medicinal plants in aquaculture and their action mechanisms: A review

“…Accumulation of free radicals in tissue can result in chronic diseases associated with cancer, cardiovascular disease, diabetes and arthritis. It has been reported that some of the ethnomedicinal plants such as Cinnamon zeylanicum , Andrographis paniculata , Eugenia polyantha , Curcuma xanthorrhiza , Angelica sinensis and Orthosiphon stamineus are proven to fight various illnesses ranging from a common fever to metabolic disease in Asian regions 65,66 . Herbal plants contain a considerable amount of antimicrobial substances potentially utilised as herbal medications to fight a wide range of pathogenic microbes 67 .…”

“…It has been reported that some of the ethnomedicinal plants such as Cinnamon zeylanicum, Andrographis paniculata, Eugenia polyantha, Curcuma xanthorrhiza, Angelica sinensis and Orthosiphon stamineus are proven to fight various illnesses ranging from a common fever to metabolic disease in Asian regions. 65,66 Herbal plants contain a considerable amount of antimicrobial substances potentially utilised as herbal medications to fight a wide range of pathogenic microbes. 67 Different plants contain considerable bioactive compounds, including steroids, proteins, tannins, saponins, terpenoids and alkaloids.…”