2018
DOI: 10.17268/sci.agropecu.2018.02.06
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The extract of Caesalpinia spinosa inhibits the in vivo infection of Flavobacterium columnare in tilapia

Abstract: En la presente investigación se realizó el ensayo in vivo del extracto de C. spinosa como un controlador de F. columnare en individuos de tilapia. Para lo cual, se obtuvo el extracto de frutos secos de C. spinosa y se mezcló con el agua de cultivo para peces a la concentración final de 0.14 mg/ml en acuarios de 280 l. En la primera etapa, los peces de tilapia infectados artificialmente con F. columnare manifestaron los síntomas de la enfermedad. En la segunda etapa, los peces enfermos fueron tratados con el ex… Show more

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“…If such compounds cross the membrane, due to changes in the membrane potential or other mechanisms that alter its permeability, as is the case with tumor cells, the C. spinosa extract, upon entering the intracellular environment, may induce apoptosis and cell death (Figure 7). This proposal could be explained by the results of Gomez-Cadena et al (2016), Prieto et al (2018, who reported a reduction in tumors in mice treated with the C. spinosa ethanolic extract.…”
Section: In Vivo Acute Toxicity Test and Chronic Toxicity Test Of C Spinosa In O Niloticusmentioning
confidence: 98%
See 1 more Smart Citation
“…If such compounds cross the membrane, due to changes in the membrane potential or other mechanisms that alter its permeability, as is the case with tumor cells, the C. spinosa extract, upon entering the intracellular environment, may induce apoptosis and cell death (Figure 7). This proposal could be explained by the results of Gomez-Cadena et al (2016), Prieto et al (2018, who reported a reduction in tumors in mice treated with the C. spinosa ethanolic extract.…”
Section: In Vivo Acute Toxicity Test and Chronic Toxicity Test Of C Spinosa In O Niloticusmentioning
confidence: 98%
“…Previous studies have demonstrated that the aqueous extract of tara has an IC 50 value of antioxidants greater than that of ascorbic acid (Callohuari et al, 2017) and is able to control the degradation of hyaluronan (Valachová et al, 2014). In addition to the antioxidant profile, C. spinosa extract contains active compounds for the control of gram-positive and gram-negative bacteria, established by in vitro (Aguilar-Galvez et al, 2014) and in vivo treatment of tilapia infected with Flavobacterium columnare (Prieto et al, 2018). From the isolation of the bioactive fraction of the extract, two compounds, methyl gallate and gallic acid, were identified as responsible for the bacterial inhibition of Salmonella typhi, Listeria monocytogenes, and Staphylococcus aureus (Olmedo-Juárez et al, 2019).…”
Section: Introductionmentioning
confidence: 99%