The external phenotype of aging

Microfocused Ultrasound with Visualization for Face Slimming: Preliminary Results in Four Women

“…Additionally, the visual effect of a slim face in its middle third improves the appearance due to sustained Yarbus triangle appearance. 1 , 3 …”

“…Furthermore, sagging cheeks caused by alterations in subcutaneous adipose layers of the face and loss of skin elasticity are also considered signs of aging faces and may cause concerns, especially in women. 3 …”

“…2 Furthermore, sagging cheeks caused by alterations in subcutaneous adipose layers of the face and loss of skin elasticity are also considered signs of aging faces and may cause concerns, especially in women. 3 To minimize these effects, many patients search for dermatologists and plastic surgeons to perform aesthetic procedures aimed at normalizing the appearance to the Yarbus triangle and other facial treatments. Surgical procedures, such as buccal fat pad removal (bichectomy), have been indicated, despite higher risks than noninvasive procedures.…”

Changes in Computer-Analyzed Facial Expressions with Age

“…On upper facial expression, namely AU 06 and 07, the older adults can show greater intensity than the younger adults. Increased activity in orbicularis oculi muscle [ 81 ], deeply set of eye [ 82 ], and changes in eyelid due to poor visual acuity [ 83 ] may have affected the changes in upper facial expression. For lower facial expression, AU 10, 12, 14, the strength of the face may have been further tapped due to the highlighted facial contour caused by loss of subcutaneous fill around the nose and mouth in the older adults [ 84 ].…”

Lack of resemblance between Myhre syndrome and other “segmental progeroid” syndromes warrants restraint in applying this classification

“…Several of the adults we follow have been reported [4][5][6], but we have not observed signs of accelerated aging. In fact, several adults over the age of 30 years appear younger than their chronological ages and do not manifest the defining phenotypic features of aging [7]. Several of the clinical features in the individual reported by Kandhaya-Pillai and colleagues are typical of adults with Myhre syndrome (tight skin of extremities, short stature, hearing loss).…”