The extent and nature of disability in different urticarial conditions

Poon, Emily; Seed, Paul; Greaves, Malcolm W.; Kobza-Black, A.

doi:10.1046/j.1365-2133.1999.02767.x

Cited by 188 publications

(145 citation statements)

References 15 publications

(24 reference statements)

Supporting

Mentioning

129

Contrasting

Unclassified

Order By: Relevance

“…11,14 Studies have shown that the degree to which quality of life is affected in patients with chronic urticaria may vary in accordance with the different clinical types of the disease, and may in some aspects even become disabling. 15 The degree to which quality of life is impaired in these patients was found to be similar to that experienced by coronary patients with triple vessel coronary artery disease, principally with respect to psychological aspects and social relationships. 9 The objective of the present study was to assess the impact of chronic urticaria on patients' quality of life and to clarify which domains were more severely affected in these patients.…”

Section: Introductionmentioning

confidence: 75%

“…These findings are in agreement with data published in the literature. 15,28,30 In the present study, the SF-36 domains indicative of greater impairment of quality of life were: rolephysical and vitality. The role-physical domain reflects 24,26 In the comparison of the scores of the questionnaires between the clinical types of chronic urticaria (COU, PU and MU), no statistically significant differences were found between the various types and it was impossible to conclude whether one may affect quality of life to a greater extent than another.…”

Section: 28-30mentioning

confidence: 98%

“…Other studies based on the same instruments have shown similar results. 15,[24][25][26][27] The patients selected for this study were recruited at a dermatology outpatient clinic specializing in urticaria. The clinic is linked to a university that is a reference in tertiary healthcare.…”

Section: Discussionmentioning

confidence: 99%

“…The role-physical domain reflects 24,26 In the comparison of the scores of the questionnaires between the clinical types of chronic urticaria (COU, PU and MU), no statistically significant differences were found between the various types and it was impossible to conclude whether one may affect quality of life to a greater extent than another. In the literature, O'Donnel et al (1997) and Poon et al (1999) described poorer quality of life in patients with delayed pressure urticaria and cholinergic urticaria. 9,15 In both these studies, sample sizes were larger than that of the present study.…”

Section: 28-30mentioning

confidence: 99%

See 3 more Smart Citations

Estudo da qualidade de vida nos pacientes com urticária crônica

Souza

Rotta

et al. 2011

An. Bras. Dermatol.

View full text Add to dashboard Cite

BACKGROUND: Chronic urticaria affects patients by interfering with their daily activities, damaging their self-esteem and negatively affecting their interpersonal relationships. Healthcare professionals may underestimate the impact of the condition on patients' quality of life. OBJECTIVES: To evaluate quality of life using one generic and one disease-specific health-related quality of life instrument; to compare quality of life between the different clinical types of chronic urticaria and to evaluate whether angioedema further impairs quality of life. METHODS: Sixty-two patients with chronic urticaria, who had had signs or symptoms of the disease within the preceding week, were divided into groups according to whether they had ordinary chronic urticaria, physical chronic urticaria or mixed chronic urticaria. RESULTS: There was a predominance of women in this study (72.6%). The mean age of patients was 39.8 years and angioedema was associated with chronic urticaria in 75.8% of cases. Associated angioedema was more commonly found in patients with ordinary chronic urticaria (p=0.011) and in women (p=0.024). With respect to the different clinical types, 32.3% of the patients had ordinary chronic urticaria, 27.4% had physical chronic urticaria and 40.3% had mixed chronic urticaria. Mean overall score for the disease-specific questionnaire was 10.4. In this questionnaire, the most affected domains were "symptoms and feelings" and "daily activities", while the most affected domains in the SF-36 were "physical role" and "vitality". Quality of life was found to be impaired in women, in patients of up to 30 years of age, in those attending a first consultation, in those with higher education levels, in patients who had had the disease for up to one year and in those with angioedema. CONCLUSIONS: Chronic urticaria affects quality of life, as measured using a disease-specific questionnaire and a generic questionnaire. There was no statistically significant difference between the clinical types. The presence of angioedema impaired patients' quality of life even further. There was a statistically significant correlation between the scores obtained using the disease-specific questionnaire and those obtained using the generic questionnaire. Keywords: Angioedema; Quality of life; Questionnaires; Sickness impact profile; Urticaria Resumo: FUNDAMENTOS: A urticária crônica compromete o doente por interferir nas atividades diárias, prejudicar a autoestima e as relações interpessoais. Os profissionais de saúde subestimam seu impacto na qualidade de vida dos doentes. OBJETIVOS: Avaliar a qualidade de vida com questionário específico e genérico. Compará-la entre os tipos clínicos de urticária crônica e avaliar se o angioedema piora a qualidade de vida. MÉTODOS: Participaram 62 doentes com urticária crônica, com sinais e sintomas da doença até 7 dias da consulta, que foram divididos em urticária crônica comum, urticária crônica física e urticária crônica mista. RESULTADOS: Observou-se predominância de mulheres (72,6%), idade m...

show abstract

Section: Introductionmentioning

confidence: 75%

Section: 28-30mentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Section: 28-30mentioning

confidence: 99%

See 2 more Smart Citations

Estudo da qualidade de vida nos pacientes com urticária crônica

Souza

Rotta

et al. 2011

An. Bras. Dermatol.

View full text Add to dashboard Cite

show abstract

“…Además, entre los pacientes afectados se ha observado un incremento del factor de necrosis tumoral alfa (TNF-α) y de la interleucina 1-beta (IL-1β) en suero y en las capas basales de la epidermis no afectada. También, se ha sugerido que los derivados del ácido araquidónico están implicados, pero esto no se ha podido comprobar (12,14). También, se han asociado otros neuropéptidos, como la sustancia P y el péptido relacionado con el gen de la calcitonina.…”

Section: Urticaria Por Presiónunclassified

Urticaria inducible: serie de casos y revisión de la literatura

Amaya

Sánchez

2015

biomedica

View full text Add to dashboard Cite

Contribución de los autores:Jorge Sánchez: idea central del artículo Todos los autores contribuyeron por igual en la redacción y revisión del manuscrito. Las urticarias inducibles constituyen un grupo heterogéneo de trastornos cutáneos caracterizados por la aparición de habones, prurito o angioedema, que en ocasiones se acompañan de síntomas sistémicos causados por estímulos inocuos para la mayoría de la población, como el frío, el calor, la presión, etc., y que comprometen la calidad de vida de los pacientes. La mayor parte de la literatura médica pertinente proviene de reportes y series de casos, ya que su epidemiología se ha estudiado poco. El objetivo de esta revisión es ofrecer una visión actualizada de la información disponible sobre varios tipos de urticaria inducida, mediante la presentación de un caso clínico ilustrativo y la descripción de los mecanismos fisiopatológicos, las manifestaciones clínicas y el tratamiento de cada condición. Urticaria inducible: serie de casos y revisión de la literaturaPalabras clave: alergia e inmunología, angioedema, enfermedades de la piel, urticaria, edema doi: http://dx.doi.org/10.7705/biomedica.v36i1.2678 Inducible urticaria: Case series and literature reviewInducible urticaria is a heterogeneous group of skin disorders characterized by the appearance of wheals, pruritus and/or angioedema, sometimes accompanied by systemic symptoms caused by innocuous stimuli (cold, heat, pressure, etc.). This group of disorders compromises people's quality of life and most of the literature in this regard comes from case reports and case series since its epidemiology has been poorly studied and some cases are very rare. The aim of this review is to show an up-to-date overview of the available literature for various types of inducible urticarias, always beginning with an illustrative case and then describing their pathophysiological mechanisms, clinical manifestations, and treatment. La urticaria es una enfermedad cutánea y de las mucosas caracterizada por la aparición de habones o angioedema que es preciso diferenciar de otras condiciones médicas en las que pueden presentarse habones, angioedema o los dos, por ejemplo, la anafilaxia, los síndromes autoinflamatorios o el angioedema hereditario (1). Según su duración se ha clasificado en aguda y crónica, definiéndose esta como aquella con una duración mayor a seis semanas. La prevalencia de la urticaria crónica se estima entre 0,5 y 5 % de la población general. Según algunos estudios, en la población estadounidense la incidencia es de 1,4 % por año, aproximadamente (2). La European Academy of Allergy and ClinicalImmunology (EAACI) ha propuesto recientemente una clasificación etiológica más acorde con el conocimiento actual de los mecanismos subyacentes de la enfermedad, que incluye bajo el nombre de "urticaria inducible" aquellas desencadenadas por estímulos físicos comúnmente inocuos como, por ejemplo, el calor, el frío, la presión aplicada a la piel, el ejercicio, la vibración, la luz solar y los

show abstract

The comparative burden of chronic spontaneous urticaria, atopic dermatitis and psoriasis in five European countries

Balp,

Krupsky,

Gupta

et al. 2024

JEADV Clinical Practice

View full text Add to dashboard Cite

BackgroundSkin diseases can have a significant impact on the physical, psychological and social well‐being of patients. Quantification of the burden of chronic spontaneous urticaria (CSU) compared to other dermatological conditions is limited.ObjectivesTo evaluate the comparative humanistic and economic burden of CSU, atopic dermatitis (AD), and psoriasis (PSO) in five European countries (EU5).MethodsThis cross‐sectional analysis compared data from adult respondents with a physician diagnosis of CSU, AD and PSO from the 2020 National Health and Wellness Survey in EU5 (France, Germany, Italy, Spain and the United Kingdom). Outcomes included Short Form (SF)‐12v2 [mental (MCS) and physical component (PCS) summary scores], SF‐6D, EQ‐5D, EQ‐Visual Analogue Scale (VAS), Dermatology Life Quality Index (DLQI), General Anxiety Disorder‐7 (GAD‐7), Patient Health Questionnaire‐9 (PHQ‐9), Work Productivity and Activity Impairment (WPAI) and healthcare resource utilization (HRU). Multivariable analyses comparing CSU to AD and PSO, respectively, were conducted for each outcome.ResultsThis analysis included 379 CSU, 788 AD and 2,636 PSO patients. Adjusted MCS and PCS scores were lower among CSU patients than AD (MCS, p = 0.006; PCS, p < 0.001) and PSO (p < 0.001 for all). SF‐6D and EQ‐5D scores were consistently lower among CSU patients versus AD and PSO (p < 0.001 for all), whereas the EQ VAS was lower in CSU cohort versus PSO cohort (p = 0.003). Higher DLQI scores were reported in the CSU cohort versus AD and PSO (p < 0.001 for both) and the proportion of patients with anxiety and depression, respectively, (GAD‐7 and PHQ‐9 scores ≥5) was greater among the CSU cohort versus AD and PSO (p < 0.001 for all). Finally, higher HRUs and worse WPAI scores (p < 0.005) were observed in the CSU cohort relative to AD and PSO cohort.ConclusionsCSU is associated with significantly worse health‐related quality of life, more mental comorbidities, negative impact on patients' daily lives and the ability to work, ultimately leading to higher HRU compared with AD and PSO.

show abstract

The extent and nature of disability in different urticarial conditions

Cited by 188 publications

References 15 publications

Estudo da qualidade de vida nos pacientes com urticária crônica

Estudo da qualidade de vida nos pacientes com urticária crônica

Urticaria inducible: serie de casos y revisión de la literatura

The comparative burden of chronic spontaneous urticaria, atopic dermatitis and psoriasis in five European countries

Contact Info

Product

Resources

About