The Expression of Tumor Necrosis Factor-Alpha Specifically Stimulated with Antigenic Epitope of E6 Human Papillomavirus Type 16 in Cervical Cancer

Mechanism of TNF- α inducing apoptosis and autophagy of chondrocytes by activating NF- κ B signal pathway

“…As part of the pathological process of OA, many inflammatory mediators can induce the release of different types of inflammatory mediators, and further cause a cascade of inflammatory reactions around chondrocytes. TNF-α is the key factor inducing the disease (8,9). Clinical studies have shown that blocking the expression of TNF-α is beneficial in alleviating the degeneration of extracellular matrix in human chondrocytes.…”