The Expression of CD2 in Chronic HBV Infection

Predictive model for inflammation grades of chronic hepatitis B: Large‐scale analysis of clinical parameters and gene expressions

“…23 The AST positive specific-related gene CD58 ( Figure 3B) was also found related to the microtubule and immune response system and significantly increased with the severity of HBV infection. 24 Intriguingly, by utilizing interferon-stimulated genes datasets (Interferome: http://interferome.its.monash.edu.au), we found seven interferon-stimulated genes that are significantly correlated with serum HBV-DNA. MKX, TSNARE1 and EFR3A are positively and ACSF3, H2AFJ, XRN1 and ZNF677 are negatively correlated with the increasing value of serum HBV-DNA in infected hepatocytes.…”

“…Additionally, in the HBV‐DNA network (Figure C), a core significant gene SLC9A3R2 , co‐expressing with ACACB and SP1 , is a membrane transporter of HBV and HDV entry . The AST positive specific‐related gene CD58 (Figure B) was also found related to the microtubule and immune response system and significantly increased with the severity of HBV infection . Intriguingly, by utilizing interferon‐stimulated genes datasets (Interferome: http://interferome.its.monash.edu.au), we found seven interferon‐stimulated genes that are significantly correlated with serum HBV‐DNA.…”