2014
DOI: 10.1155/2014/953203
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The Expression of Bcl-2 and BID in Gastric Cancer Cells

Abstract: Background. Bcl-2 and BID play a major role in the process of apoptosis and their dysfunction underlies carcinogenesis. The study objective was to assess the expression of Bcl-2 and BID in gastric cancer cells in correlation with chosen clinicopathological parameters, presence of Helicobacter pylori infection, and patients' survival. Materials and Methods. The study involved 88 patients operated on for gastric cancer. The expressions of Bcl-2 and BID were determined immunohistochemically. Results. Positive Bcl… Show more

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Cited by 38 publications
(33 citation statements)
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“…Attempts to correlate Ki67 and BCL2 with clinicopathologic parameters have yielded contradictory results in gastric cancer. Earlier studies demonstrated that BCL2 correlates to intestinal type rather than diffuse or mixed type and plays an important role in tumor growth of the intestinal type in gastric cancer [29,30]. Müller et al [31] reported a significant relationship between tumor cell proliferation and intestinal type, but no significant correlation between Ki67 and survival.…”
Section: Discussionmentioning
confidence: 99%
“…Attempts to correlate Ki67 and BCL2 with clinicopathologic parameters have yielded contradictory results in gastric cancer. Earlier studies demonstrated that BCL2 correlates to intestinal type rather than diffuse or mixed type and plays an important role in tumor growth of the intestinal type in gastric cancer [29,30]. Müller et al [31] reported a significant relationship between tumor cell proliferation and intestinal type, but no significant correlation between Ki67 and survival.…”
Section: Discussionmentioning
confidence: 99%
“…Due to its aggregation in the target area with low radiation to the surrounding normal tissue and the profile of quick attenuation of radiation, 125 I radioactive particle is recognized as a potent tool in lung cancer treatment. CT guidance can obviously reduce operating time and radiation dose, and elevate puncture accuracy, resulting in small trauma, apparent curative effect, rapid recovery, and fewer adverse reactions [23,24]. This study retrospectively compared the effect of CT-guided 125 I radioactive particles and chemotherapy in the treatment of NSCLC.…”
Section: Discussionmentioning
confidence: 99%
“…No. 352001) [59]. Simultaneously, it was also streaked on a BHI agar plate containing the same concentration of FBS and antibiotics.…”
Section: Culture Of Clinical Isolates In Liquid and Solid Growth Mediummentioning
confidence: 99%
“…The isolated H. pylori strains were analyzed for the growth pattern until 24 h. In brief, the isolates were cultured in a 14 ml round bottom snap cap tube (BD) in biological duplicates by setting initial OD 600 0.05, which correspond to approximately 80 million CFU per ml [59]. Further, they were incubated in the microaerophilic chamber, as mentioned above.…”
Section: Growth Curvementioning
confidence: 99%
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