The Exploration and Practice of Remote Ischemic Preconditioning Through Intermittent Seiza

Abstract

Objectives: To measure and compare the tissue oxygenation of gastrocnemius during ischemic and reperfusion (I&R) to lower limbs through two different ways; establish a method for remote ischemic preconditioning(RIPC) through intermittent Seiza and observe its effect on capillary fragility of forearm skin. Methods: 12 college students participated in the measurement of tissue oxygenation in gastrocnemius (using ANT+,MOXY-3) during I&R either through intermittent Seiza or blood pressure cuff inflated to 200 mmHg around thigh , taken 5 min reperfusion following 5 min ischemia as a cycle, repeat 3 such cycles in one RIPC. Check the capillary fragility in the forearm of 33 students whom were in either experimental or control group at pre-, 2 weeks and 4 weeks after the daily intermittent Seiza RIPC or not. Results: Tissue oxygenation in gastrocnemius at 1,3,5 minute of ischemic decreased significantly during both ways compared with before ischemic, but intermittent Seiza can make it decrease more rapidly and thoroughly than that of blood pressure cuff inflation. The forearm skin capillary fragility reduced significantly compared with that of the control group after 4 weeks daily intermittent Seiza RIPC. Conclusions: Intermittent Seiza is an effective and easy way for RIPC, and can improve the quality of skin capillary after 4 weeks daily practice.