Abstract:Rabbit anti-thymocyte globulin (ATG) given with conditioning for allogeneic haematopoietic stem cell transplantation (alloHSCT) is effective in reducing the risk of chronic graft-versus-host disease (cGVHD). Whether conventional risk factors for cGVHD apply to ATG-conditioned alloHSCT is not known. Between the years 2004 and 2011, 356 adults (median age 48) from 3 centres received 4.5 mg/kg of Thymoglobulin prior to alloHSCT for haematologic malignancy (acute leukaemia 58%, chronic myeloid leukaemia 6%, other … Show more
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