“…NFIX duplication has also been observed in a few individuals presenting ID, short stature, small head circumference, and minor dysmorphic features (Dolan et al, 2010 ; Trimouille et al, 2018 ). Recently, haploinsufficiency of NFIB (caused by either deletions of 9p23‐p22.2 or NFIB sequence variations), has been shown to cause ID with macrocephaly, along with motor delay, hypotonia, behavioral abnormalities, and variable structural brain anomalies mainly involving the corpus callosum (Barrus et al, 2020 ; Schanze et al, 2018 ).…”