In this paper, we study boundary value problems of nonlinear fractional differential equations in a Banach Space E of the following form:where D 0 + denotes the Caputo fractional derivative, 0 < p, q ≤ 1. Some new results on the solutions are obtained, by the concept of measures of noncompactness and the fixed point theorem of Mönch type.MSC 2010 : 34B37, 34K10, 34L15, 34L30, 34A45