The Excretion and Retention of Ingested Lithium and Its Effect on the Ionic Balance of Man

Trautner, E. M.; Morris, R. J. H.; Noack, Carolin; Gershon, Samuel

doi:10.5694/j.1326-5377.1955.tb44990.x

Cited by 149 publications

(32 citation statements)

References 19 publications

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“…Decreased excretion of lithium in a patient receiving optimal subtoxic therapeutic dosage, due to either reduced sodium or water intake, or to intercurrent illness, especially with reduced urine output (Trautner et al, 1955).…”

Section: Discussionmentioning

confidence: 99%

Acute lithium poisoning

Gaind

Saran

1970

Postgraduate Medical Journal

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Section: Discussionmentioning

confidence: 99%

Acute lithium poisoning

Gaind

Saran

1970

Postgraduate Medical Journal

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“…Earlier reports (Trautner et al 1955;Gershon and Yuwiler 1960) and more recent ones (Greenspan et al 1968;Serry 1969) suggest that manic patients metabolize lithium in a unique manner. For example, manic patients are said to retain the lithium ion and to excrete it more slowly than normothymic subjects (Trautner et al 1955;Gershon and Yuwiler 1960;Greenspan, Green, and Durrell 1968).…”

Section: Distribution Of Lithium In Biological Fluids Lithium Is Read-mentioning

confidence: 94%

“…Based on pharmacological studies concerning the retention and excretion of the lithium ion (Trautner et al 1955), the treatment outline consists of stabilization and maintenance.…”

Section: Lithium Saltsmentioning

confidence: 99%

“…For example, manic patients are said to retain the lithium ion and to excrete it more slowly than normothymic subjects (Trautner et al 1955;Gershon and Yuwiler 1960;Greenspan, Green, and Durrell 1968). The increased retention may be due to a relative shift to an intracellular location (Greenspan, Green, and Durrell 1968;Shopsin, Gershon, and Pinkney 1969).…”

Section: Distribution Of Lithium In Biological Fluids Lithium Is Read-mentioning

confidence: 99%

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Brain Chemistry and Mental Disease

Ho¹,

McIsaac²

1971

Advances in Behavioral Biology

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PREFACEThis volume contains the proceedings of the fourth international symposium held in November 1970 at the Texas Research Institute of Mental Sciences in Houston. Leading psychiatrists, biochemists, and pharmacologists from the United States and Great Britain presented new material and reviewed current concepts concerning schizophrenia and the affective disorders, with particular reference to the neurochemical basis of the etiology and chemotherapy of these diseases.Although the multiple mechanisms of mental disease are still not fully understood, substantial progress has definitely been made. The greatest contribution has come through the development of new therapeutic agents that not only provide invaluable help to the mentally ill but serve as chemical tools for studying the biological mechanisms associated with the disease state. Studies concerning the proposed catecholamine and indolealkylamine hypotheses for affective disorders and the possible formation of endogenous. toxins in schizophrenia have stimulated significant new research.This book presents new studies of schizophrenia and the affective disorders in one volume. It is our hope that it represents an effective integration of basic biochemical and pharmacological research with current clinical findings and that it will increase understanding of the etiology of mental disease and provide an impetus for the development of more effective therapeutic agents.We thank Drs.

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“…Trautner continued with his interest in the physiology and pharmacology of lithium and a young Melbourne psychiatrist, Samuel Gershon, soon joined him in a productive research collaboration [34]. Gershon later moved to Michigan where he initiated an active lithium research program that was l a rgely responsible for stimulating US interest in this medication [35].…”

Section: Subsequent Australian Researchmentioning

confidence: 99%

On the 50th Anniversary of John Cade's Discovery of the Anti-Manic Effect of Lithium

Mitchell

1999

Aust N Z J Psychiatry

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The Excretion and Retention of Ingested Lithium and Its Effect on the Ionic Balance of Man

Cited by 149 publications

References 19 publications

Acute lithium poisoning

Acute lithium poisoning

Brain Chemistry and Mental Disease

On the 50th Anniversary of John Cade's Discovery of the Anti-Manic Effect of Lithium

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