The EXCITE Trial

Abstract

Objective This is the first study to examine Wolf Motor Function Test (WMFT) tasks among EXCITE Trial participants that could not be completed at baseline or 2 weeks later. Methods Data were collected from participants who received constraint-induced movement therapy (CIMT) immediately at the time of randomization (CIMT-I, n = 106) and from those for whom there was a delay of 1 year in receiving this intervention (CIMT-D, n = 116). Data were collected at baseline and at a 2-week time point, during which the CIMT-I group received the CIMT intervention and the CIMT-D group did not. Generalized estimating equation (GEE) analyses were used to examine repeated binary data and count values. Group and visit interactions were assessed, adjusting for functional level, affected side, dominant side, age, and gender covariates. Results In CIMT-I participants, there was an increase in the proportion of completed tasks at posttest compared with CIMT-D participants, particularly with respect to those tasks requiring dexterity with small objects and total incompletes (P < .0033). Compared with baseline, 120 tasks governing distal limb use for CIMT-I and 58 tasks dispersed across the WMFT for CIMT-D could be completed after 2 weeks. Common movement components that may have contributed to incomplete tasks include shoulder stabilization and flexion, elbow flexion and extension, wrist pronation, supination and ulnar deviation, and pincer grip. Conclusion CIMT training should emphasize therapy for those specific movement components in patients who meet the EXCITE criteria for baseline motor control.

Correlations between statistical models of robotically collected kinematics and clinical measures of upper extremity function

“…UE function is a varied and complex set of behaviors with a multitude of factors affecting the ability to use an impaired UE in the real world. Clinical measurements of function typically produce fairly volatile results with patients performing extremely well during the performance of a single repetition of an activity and then poorly on the next[2]. In addition, these clinical tests typically produce a single piece of information describing a single aspect of movement, necessitating a wide variety of tests to be performed to produce a data set that will reflect the whole of UE ability.…”

Motor Rehabilitation after Stroke

“…What are the factors (e.g., the time for delivering a specific intervention, patient characteristics) that may affect treatment outcomes [ 3 , 4 ]?…”