The Evolving Landscape of Gout in the Female: A Narrative Review
Jennifer Lee,
Nicholas Sumpter,
Tony R. Merriman
et al.
Abstract:Gout is at least three times more prevalent in males than in females. However, concurrent with rising total gout prevalence, complex factors, including comorbidities, diet, lifestyle, and aging, have promoted higher gout prevalence in females. This narrative review focuses on summarizing recent developments in the landscape of gout in females and the mechanisms involved. New knowledge on sex hormone effects on both urate-excreting and urate-reabsorbing transporters and higher hypertension and chronic kidney di… Show more
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