NASA Extreme Environment Mission O perations (NEEMO) is an underwater spaceflight analog that allows a true mission-like operational environment and uses buoyancy effects and added weight to simulate different gravity levels. Three missions were undertaken from 2014-2015, NEEMO 18-20. All missions were performed at the Florida International University's Aquarius Reef Base, an undersea research habitat. During each mission, the effects of communication latencies on operations concepts, timelines, and tasks were studied. METHO DS: Twe lve subje cts (4 pe r mission) we re we ighed out to simulate near-zero or partial gravity extravehicular activity (EVA) and evaluated different operations concepts for inte gration and management of a simulated Earth-based science te am (ST) to provide input and dire ction during e xploration activities. Exploration traverses were preplanned based on precursor data. Subjects completed science-related tasks including presampling surveys, geologic-based sampling, and marine-based sampling as a portion of their tasks on saturation dives up to 4 hours in duration that were designed to simulate EVA on Mars or the moons of Mars. One-way communication latencies, 5 and 10 minutes between space and mission control, were simulated throughout the missions. O bjective data included task completion times, total EVA times, crew idle time, translation time, ST assimilation time (defined as time available for ST to discuss data/imagery after data acquisition). Subjective data included acceptability, simulatio n quality, capability assessment ratings, and comments. RESULTS : Precursor data can be used effectively to plan and execute e xploration trave rse EVAs (plans included de tailed location of science sites, high-fidelity imagery of the sites, and directions to landmarks of interest within a site). O perations concepts that allow for presampling surveys enable efficient traverse execution and meaningful Mission Control Center (MCC) inte raction across communication late ncies and can be done with minimal crew idle time. Imagery and contextual information from the EVA crew that is transmitted real-time to the intravehicular activity (IVA) crewmember(s) can be used to verify that exploration traverse plans are being executed correctly. That same data can be effectively used by MCC (across comm latency) to provide meaningful feedback and instruction to the crew regarding sampling priorities, additional tasks, and changes to the EVA timeline. Text / data capabilities are preferred over voice capabilities between MCC and IVA when executing exploration traverse plans over communication latency.