2005
DOI: 10.1016/j.det.2004.09.009
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The Evolution of Soft Tissue Fillers in Clinical Practice

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Cited by 106 publications
(110 citation statements)
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“…HA is in vivo mainly degraded through hydrolysis catalyzed by hyaluronidases giving safe products. It has been estimated that the half-life of HA in the skin is about 24h, in the eye 24-36h, in the cartilage 1-3 weeks and 70 days in the vitreous humor (Laurent & Reed, 1991;Stern et al, 2007;Murray et al, 2005). Because of the above highlighted properties, the development and commercialization of HA based products are in continuous intensification (Widner et al, 2005).…”
Section: Hyaluronan Applicationsmentioning
confidence: 99%
“…HA is in vivo mainly degraded through hydrolysis catalyzed by hyaluronidases giving safe products. It has been estimated that the half-life of HA in the skin is about 24h, in the eye 24-36h, in the cartilage 1-3 weeks and 70 days in the vitreous humor (Laurent & Reed, 1991;Stern et al, 2007;Murray et al, 2005). Because of the above highlighted properties, the development and commercialization of HA based products are in continuous intensification (Widner et al, 2005).…”
Section: Hyaluronan Applicationsmentioning
confidence: 99%
“…4,5 The first of these, medical grade fluid silicone of 350 centistokes (cS), was manufactured by Dow Corning, Inc., from 1954 to 1992, but banned by the U.S.…”
Section: Dermal Fillersmentioning
confidence: 99%
“…In selected individuals, soft tissue filler injections can provide an immediately visible result in the convenience of the office setting, and the procedure is minimally invasive and has a good safety record. Despite its temporary longevity, it is popular because it is simple, effective, and economical [2,3].…”
mentioning
confidence: 99%