The evolution of diastolic function during liver transplantation

Devauchelle, Pauline; Schmitt, Z.; Bonnet, A.; Duperret, S.; Viale, Jean–Paul; Mabrut, Jean‐Yves; Aubrun, Frédéric; Genête, Mathieu

doi:10.1016/j.accpm.2016.09.009

Cited by 6 publications

(10 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Out of 1149 articles 91 were selected for full text review. As many as 16 articles that met the predefined eligibility criteria were included in the final analysis[15,16,21,22,24-26,31-39]. The process of identification, screening and eligibility is described in Figure 1.…”

Section: Resultsmentioning

confidence: 99%

“…The difference in means of MELD scores between LVDD groups and in patients without LVDD was estimated in 8 studies[21,24,32,33,34,36,38,39] (Table 6). Two studies found that patients from the grade 2 LVDD subgroup had a higher MELD score, compared to patients with grade 1 LVDD and without LVDD ( P < 0.01 and P < 0.005, respectively)[21,36].…”

Section: Resultsmentioning

confidence: 99%

“…Two studies found that patients from the grade 2 LVDD subgroup had a higher MELD score, compared to patients with grade 1 LVDD and without LVDD ( P < 0.01 and P < 0.005, respectively)[21,36]. The means of MELD scores did not markedly differ in patients with and without LVDD in remaining 6 studies[24,32,33,34,38,39].…”

Section: Resultsmentioning

confidence: 99%

“…LVDD was associated with an older age in 4 studies[32-35]. On the contrary, 6 studies found that LVDD was not associated with an older age but there was no evidence of age impact on LVDD in all these studies[21,22,24,31,38,39].…”

Section: Resultsmentioning

confidence: 99%

“…Kazankov et al[38] investigated that there was no difference in cardiac and liver function among the patients treated or not treated with β-blockers. Devauchelle et al[39] did not notice a statistically significant difference ( P = 0.7) in using β-blockers between LVDD and no LVDD groups. Even if the influence of prophylactic treatment on LVDD was not assessed in all of our chosen studies, we think it may have had an impact on the LVDD grade.…”

Section: Discussionmentioning

confidence: 95%

See 4 more Smart Citations

Liver cirrhosis and left ventricle diastolic dysfunction: Systematic review

Stundiene¹,

Sarnelyte²,

Norkutė³

et al. 2019

WJG

View full text Add to dashboard Cite

BACKGROUND Liver cirrhosis is a chronic hepatic disease which is associated with cardiovascular abnormalities. Hyperdynamic circulation in liver cirrhosis causes functional and structural cardiac alterations. The prevalence of left ventricle diastolic dysfunction (LVDD) in cirrhotic patients ranges from 25.7% to as high as 81.4% as reported in different studies. In several studies the severity of diastolic dysfunction (DD) correlated with a degree of liver failure and the rate of dysfunction was higher in patients with decompensated cirrhosis compared with compensated. Future directions of comprehensive assessment of cardiac function in cirrhotic patients might provide a better prognosis for these patients. AIM To clarify the correlation between the severity of liver cirrhosis and left ventricle diastolic dysfunction in the existing literature. METHODS Through January and February of 2019 at Vilnius University we conducted a systematic review of the global existing literature on the prevalence of left ventricle diastolic dysfunction in patients with liver cirrhosis. We searched for articles in PubMed, Medline and Web of science databases. Articles were selected by using adequate inclusion and exclusion criteria. Our interest was the outcome of likely correlation between the severity of cirrhosis [evaluated by Child-Pugh classes, Model For End-Stage Liver Disease (MELD) scores] and left ventricle diastolic dysfunction [classified according to American Society of Echocardiography (ASE) guidelines (2009, 2016)], as well as relative risk of dysfunction in cirrhotic patients. Subgroup analyses were performed to evaluate the ratio and grades of left ventricle diastolic dysfunction with respect to cirrhosis severity. RESULTS A total of 1149 articles and abstracts met the initial search criteria. Sixteen articles which met the predefined eligibility criteria were included in the final analysis. Overall, 1067 patients (out of them 723 men) with liver cirrhosis were evaluated for left ventricle diastolic dysfunction. In our systemic analysis we have found that 51.2% of cirrhotic patients had left ventricle diastolic dysfunction diagnosed and the grade 1 was the most prevalent (59.2%, P < 0.001) among them, the grade 3 had been rarely diagnosed - only 5.1%. The data about the prevalence of diastolic dysfunction in cirrhotic patients depending on Child-Pugh Classes was available from 5 studies (365 patients overall) and only in 1 research diastolic dysfunction was found being associated with severity of liver cirrhosis ( P < 0.005). We established that diastolic dysfunction was diagnosed in 44.6% of Child-Pugh A class patients, in 62% of Child B class and in 63.3% of Child C patients ( P = 0.028). The proportion of patients with higher diastolic dysfunction grades increases in more severe cirrhosis presentation ( P ...

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 95%

See 3 more Smart Citations

Liver cirrhosis and left ventricle diastolic dysfunction: Systematic review

Stundiene¹,

Sarnelyte²,

Norkutė³

et al. 2019

WJG

View full text Add to dashboard Cite

show abstract

Impact of graft reperfusion on cardiac function assessed by transesophageal echocardiography during liver transplantation: an observational retrospective study

González-Suárez,

Corbett,

Hernández-Martínez

2023

J Clin Monit Comput

View full text Add to dashboard Cite

Cardiovascular instability is common during the reperfusion phase of orthotopic liver transplantation (OLT), and some patients experience a postreperfusion syndrome (PRS). However, there are no reports comparing the cardiac dysfunction between patients with PRS and those without. Thus, the aim of this study was to evaluate cardiac dysfunction in patients exhibiting PRS. This observational retrospective study included 34 patients who underwent OLT and were monitored with transesophageal echocardiography (TEE). The right ventricular/left ventricular (RV/LV) end diastolic area, tricuspid annular plane systolic excursion (TAPSE), left ventricular ejection fraction (LVEF) by Simpson method, pulsed Doppler of the mitral valve, and tissue Doppler motion of the mitral annulus were determined. Echocardiographic measurements were registered at the beginning of surgery and at 1 and 30 min after vascular unclamping. Patients with PRS (PRS group) were identified, and their echocardiographic parameters of ventricular function were compared with those in patients without PRS (non-PRS group). To check the evolution of diastolic-systolic dysfunction, general linear model-repeated measures were estimated. No patient presented systolic/diastolic dysfunction on the basal echocardiogram. One minute after vascular unclamping, the incidence of RV dilation was 4.5 times greater in patients with PRS (Cramer´s V > 0.6), and the incidence of RV systolic dysfunction was 62.5% in patients with PRS compared to 15.40% in patients without PRS (Cramer´s V = 0.45). The incidence of LV systolic dysfunction was 25% in patients with PRS compared to 0% in those without (Cramer´s V = 0.45), and left ventricular diastolic dysfunction was 4.8 times greater in patients with PRS (Cramer´s V = 0.45). No patient presented diastolic dysfunction type III. There were significant differences between groups in the evolutionary pattern at 1 and 30 min after unclamping for RV dilation (p = 0.008) and for TAPSE (p = 0.014). Liver graft reperfusion may alter cardiac function. Cardiac dysfunction was more frequent in patients with PRS. These patients exhibited temporary dysfunction of the RV associated with a varying degree of LV diastolic-systolic dysfunction. Trial registration: clinicaltrials.gov (NCT05175534). January 03, 2022; “retrospectively registered”.

show abstract