The severity of mitral regurgitation when associated with stenosis is often doubtful after clinical electrocardiographic and standard radiological examinations are completed. By the use of the available indirect methods for the assessment of mitral regurgitation, it is often impossible to distinguish between mild and moderate regurgitation, a vital distinction when considering a closed mitral valvotomy.In the analysis of left atrial pressure tracings, attention has been directed to the height and shape of the V wave (Lagerlof and Werko, 1949;Gorlin et al., 1952; Biorck et al., 1953;Logan and Turner, 1953;Connolly et al., 1955) and to the Y descent expressed as the RY/V ratio (Owen and Wood, 1955). While the use of the Y descent provides a guide to the type of valve lesion present, an occasional case of dominant mitral regurgitation has a small systolic wave and an RY/V ratio within the stenotic range (1.7). Dye dilution techniques have been employed to assess mitral regurgitation but detection of a slight degree is difficult (Korner and Shillingford, 1955). The technique of assessing the severity of mitral regurgitation by the injection of indicator into the left ventricle, while blood is sampled simultaneously from the left atrium and from a peripheral artery, suffers from the same inaccuracies due to inadequate mixing, and the distinction of mild and moderate regurgitation is impossible (Polissar and Rapaport, 1961;Jose and Bernstein, 1962). More recently the apex cardiogram has been used, but this method is insufficiently sensitive to distinguish between mild and moderate regurgitation (Nixon and Wooler, 1963). Angiocardiography with left ventricular contrast injection offers a means of directly visualizing regurgitation into the left atrium. Biplane radiography in the antero-posterior and lateral positions using a rapid serial film changer is the method generally employed (Bjork, Lodin, and Malers, 1960;Steiner et al., 1963); oblique projections and cine-radiography have also been used (Ross and Criley, 1962).We consider that the method which most accurately assesses the various grades of regurgitation is cine-radiography following left ventricular contrast injection with the patient in the right anterior oblique position. In addition objective information is obtained concerning cusp mobility. In this paper, our experience with this technique as a pre-operative assessment for mitral valve surgery is described. We felt that the investigation would be valuable in mitral stenosis when there was clinical doubt as to the degree of regurgitation; in combined mitral and aortic valve disease when the dominant lesion was uncertain (in these a further cine-angiogram of the aortic valve was obtained following injection of contrast into the ascending aorta to assess the degree of aortic regurgitation); and in pure mitral regurgitation when there was a possibility of ruptured chordch tendinee.
SUBJECTS AND METHODSThirty-two cine-angiocardiograms were obtained in 31 patients. They represent a small proportion of all cases...