The Evaluation of Taking Iron Supplements in Children Aged 6 Months-2 Years

Karapınar, Tuba Hilkay; Bildik, Olgay; Köker, Sultan Aydın; Töret, Ersin; Oymak, Yeşim; Ay, Yılmaz; Demirağ, Bengü; Vergin, Canan

doi:10.4274/jpr.37790

Cited by 5 publications

(3 citation statements)

References 10 publications

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“…Iron salts are often used for iron supplementation and treatment; unfortunately, their regular use is sometimes interrupted by parents and children due to side effects such as nausea, vomiting, and abdominal pain. [22–24] In our study, 41.6% of the infants who used iron supplements used iron supplements with incomplete adherence, and 15.9% of the mothers stated that side effects such as vomiting, discoloration of the mouth and teeth, constipation, diarrhea, etc seen while using iron supplements were the reason for incomplete adherence to iron supplements. Different studies have shown that iron preparations other than iron salts, such as sucrosomial iron and microencapsulated iron, which have been reported to have fewer GI side effects in recent years, are preferred by some families for this reason.…”

Section: Discussionmentioning

confidence: 64%

Adherence to iron supplementation during the first year of life infants in Izmir, Turkey

Tosyali,

Koç

2024

Medicine

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To determine the prevalence of adherence to iron supplementation and the risk factors for incomplete adherence during the first year of life of infants in Izmir, Turkey. In this cross-sectional study, a total of 511 infants aged 2 to 12 months who presented to the Pediatrics outpatient clinics of Ege University Children’s Hospital were included. Mothers (n = 511) who agreed to participate in the study were interviewed face-to-face and a comprehensive questionnaire including questions about the sociodemographic characteristics of the children and the family, and their adherence to iron supplementation was administered. The data obtained from 471 (92.2%) mothers who used iron supplements for their babies were subjected to further statistical analysis. Analyses were performed with SPSS 25.0. Chi-square test was used for univariate analysis and logistic regression analysis was used to determine the independent factors associated with incomplete adherence to iron supplementation. A total of 511 mothers were surveyed. Among the infants of mothers who participated in the study, 471 (92.2%) were taking iron supplementation. Of the infants who received iron supplementation, 58.3% were given iron supplementation with complete adherence. The percentage of complete adherence with iron supplementation was 35.1% between 2 and 4 months, 66.3% between 5 and 8 months, and 52.4% between 9 to 12 months. In univariate analysis, statistically significant differences were found between complete and incomplete adherence to iron supplementation in terms of infant age, time of birth, family income, maternal education, and maternal employment status (P < .001). When the data were analyzed using multivariate analysis, only maternal education level and infant age group were found to be statistically significant independent variables for complete and incomplete adherence to iron supplementation (P < .001). In populations with a high prevalence of ID, incomplete adherence to iron supplementation is a serious risk factor for ID/IDA. Although iron supplements are routinely given to infants by the Ministry of Health in Turkey, the prevalence of complete adherence to iron supplementation is low. Therefore, in order to increase the rate of complete adherence to iron supplementation, the iron supplementation status of infants should be reviewed in detail at each health child visit and families should be informed about the importance of supplementation to prevent iron deficiency.

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Section: Discussionmentioning

confidence: 64%

Adherence to iron supplementation during the first year of life infants in Izmir, Turkey

Tosyali,

Koç

2024

Medicine

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“…In our study, it was found that infants mostly used Fe + 3 salt (43.5%) provided free of charge. The most commonly used iron salts for iron prophylaxis (Fe + 2 and Fe + 3 salts) may sometimes not be preferred by families because of side effects such as nausea, vomiting, and abdominal pain [24,25,32]. In our study, it was found that different iron preparations such as sucrosomial iron and microencapsulated iron, which have been used in recent years and reported to have fewer GI side effects, were preferred by families.…”

Section: Discussionmentioning

confidence: 66%

Use of Different Iron Preparations for Prophylaxis and Effects on Iron Status in Infancy

Tosyalı,

Demirçelik,

Bağ

et al. 2024

Healthcare

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Aim: To evaluate using different iron preparations for iron deficiency and/or iron deficiency anemia prophylaxis in infants and their iron status. Methods: In this study, we retrospectively evaluated the electronic patient records of 651 healthy children aged 9 to 13 months who met the inclusion criteria and who were followed up in pediatric follow-up outpatient clinics between January 2023 and June 2023. Results: A total of 651 children with a mean age of 11.2 ± 1.4 months, 54.7% of whom were boys, who met the inclusion criteria were included in the study; 56.5% of the children were using Fe + 3 salt and the others were using Fe + 2 salt, microencapsulated iron, or sucrosomial iron drops. After the fifth month of prophylaxis, when the effects of the iron preparations used on the mean laboratory values were evaluated, it was found that hemoglobin, serum iron, and ferritin levels were lower in sucrosomial iron and microencapsulated iron users compared to other preparations (p = 0.001). When statistically pairwise comparisons were made between the groups, hemoglobin and serum iron values were found to be lower in the group using sucrosomial iron compared to the groups using Fe + 2 and Fe + 3 salts (p < 0.0001). Hemoglobin and ferritin levels were higher in the group using Fe + 2 salt compared to both sucrosomial iron and microencapsulated iron groups (p < 0.0001). When the infants were evaluated according to iron status, it was found that 208 (31.9%) had iron deficiency. Iron deficiency was found to be less in infants of families who defined their economic status as rich and in infants who used iron regularly (p-values 0.044 and 0.001, respectively). Iron deficiency/iron deficiency anemia was observed at a higher rate in the group using sucrosomial iron and microencapsulated iron prophylaxis (p = 0.001). Conclusions: To prevent iron deficiency, it is very important to use appropriate iron preparations for prophylaxis and to feed foods with high iron content. Although we found that families were willing to use different iron preparations other than iron salts for their infants, the results presented herein indicate that the rate of iron deficiency was lower in patients using iron salts. However, randomized controlled studies are needed to determine whether these preparations are effective in iron prophylaxis in infants.

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“…Also, 6.3% were not informed by healthcare workers and 4.1% feared possible side effects indicated by their family members(15). Karapinar et al(16) found that iron prophylaxis was not initiated in 16% of children, 44.5% discontinued prophylaxis. The reasons for discontinuing prophylaxis except for discontinuation of the treatments under the doctor's control were;…”

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confidence: 99%

Use of Vitamin, Mineral and Supporting Products in Children in Adana

Barutçu¹,

Akay²,

Evliyaoğlu³

et al. 2021

acmr

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Background: To determine the frequency, methods and families' knowledge about vitamins, minerals and supplementary products in children. Methods:A questionnaire form was applied by face-to-face interviews with a total of 300 parents with children under the age of 5 who applied to the University Hospital, Training and Research Hospital and randomly selected family health centers in Adana. The demographic characteristics of the participants, their level of knowledge about preventive medication and supportive products, how they used them, and who suggested starting them were evaluated. Results:The mean age of the children included in the study was 24.3±18.1 months. The correct use rates of iron and vitamin D by the parents were 60.7% and 83.3%, respectively. 147 of the parents (49%) used at least one supportive product to their children, and multivitamin (12.5%), molasses (8.3%), cumin (7.3%), honey (6.3%), fish oil (6.3%) was observed to be among the preferred products. It was found that supportive products were most frequently started due to growth and development retardation (27.7%) with the suggestions of neighbors-close relatives (45.8%) and doctors (30.7%). Conclusions:Iron and vitamin D preparations are distributed free of charge in our country; however, we believe that the correct usage rates are not at the desired level, and more training and information should be given to healthcare professionals and parents in terms of compliance with prophylaxis and correct use. Although there is not enough data in our country regarding use of supportive products, more reliable results can be obtained with more comprehensive studies.

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The Evaluation of Taking Iron Supplements in Children Aged 6 Months-2 Years

Cited by 5 publications

References 10 publications

Adherence to iron supplementation during the first year of life infants in Izmir, Turkey

Adherence to iron supplementation during the first year of life infants in Izmir, Turkey

Use of Different Iron Preparations for Prophylaxis and Effects on Iron Status in Infancy

Use of Vitamin, Mineral and Supporting Products in Children in Adana

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