The evaluation of intra- and postoperative complications related to debulking surgery with bowel resection in patients with FIGO stage III–IV ovarian cancer

Bidziński, Mariusz; Derlatka, P.; Kubik, Paweł; Ziółkowska-Seta, Izabela; Dańska-Bidzińska, Anna; Gmyrek, Leszek; Sobiczewski, Piotr; Panek, Grzegorz

doi:10.1111/j.1525-1438.2007.00896.x

Cited by 13 publications

(9 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The difference in the survival of patients in the two groups did not achieve statistical significance (20). However, the observation that survival in the two groups was similar, following an analysis of the two types of surgical treatment in advanced ovarian cancer patients without lymphadenectomy, is significant.…”

Section: Intraoperative Complicationsmentioning

confidence: 80%

See 1 more Smart Citation

Evaluation of intraoperative and postoperative complications related to lymphadenectomy in ovarian cancer patients

Gmyrek¹,

Jońska-Gmyrek²,

Sobiczewski³

et al. 2011

Oncology Letters

View full text Add to dashboard Cite

Abstract. Assessment of the regional lymph node status is an integral part of diagnostics for ovarian cancer patients. Due to the risk of complications, lymphadenectomy for ovarian cancer patients, as a routine treatment procedure, is still a subject of controversy. Therefore, the present study aimed to evaluate the frequency and nature of intraoperative and postoperative complications in ovarian cancer patients treated with surgery. In addition, a comparison of the frequency and nature of surgical complications between patients who underwent lymphadenectomy and those who did not was carried out. A retrospective analysis of 211 consecutive ovarian cancer patients treated with surgery with pelvic and aortic lymphadenectomy (group I), and 258 ovarian cancer patients treated with surgery but without lymphadenectomy (group II) was carried out. All of the patients were treated with complementary chemotherapy. The frequency and nature of the intraoperative and postoperative complications were determined. The most frequent intraoperative complications in the two groups were haemorrhage, urinary system damage and digestive tract damage. The difference in the frequency and nature between the groups was not statistically significant (p=0.683). The most frequent postoperative complications were haemorrhage, intestinal junction dehiscence, eventrations, wound dehiscence, anaemia, wound healing complications and intestinal fistulas. Haemorrhage, eventrations and wound healing complications were more frequent in group I. The difference was statistically significant (p=0.002). Due to postoperative complications, reoperative procedures were necessary in two women in group II (0.78) and in 15 women (7.11%) in group I. The difference was statistically significant (p=0.000). In conclusion, the most frequent intraoperative complications were haemorrhage, urinary system damage and digestive tract damage. The frequency of complication was found to be similar in the two groups. A statistically significant higher rate of postoperative complications, such as haemorrhage, eventrations and wound healing complications was confirmed in the lymphadenectomy group.

show abstract

Section: Intraoperative Complicationsmentioning

confidence: 80%

“…In their study, Bidzinski et al (20) reported surgery-related complications in the two types of surgical treatment, in advanced ovarian cancer patients (FIGO III-IV). The difference in the survival of patients in the two groups did not achieve statistical significance (20).…”

Section: Intraoperative Complicationsmentioning

confidence: 99%

Evaluation of intraoperative and postoperative complications related to lymphadenectomy in ovarian cancer patients

Gmyrek¹,

Jońska-Gmyrek²,

Sobiczewski³

et al. 2011

Oncology Letters

View full text Add to dashboard Cite

show abstract

“…However, in the last mentioned paper, a high rate of colostomies brings attention. In 2007, we reported our initial experience in performing rectosigmoid resection or colectomy in patients with FIGO stage III and IV ovarian cancer [ 9 ]. Our series from 2007 consisted of 39 patients treated in a single center.…”

Section: Discussionmentioning

confidence: 99%

“…A few series of extended surgical procedures including abdominal and diaphragmatic peritonectomy, partial liver resection, and partial pancreatectomy or splenectomy have been published. The resections of parts of the digestive tract, especially the large bowel, are increasingly commonly performed [ 7 – 9 ]. According to the authors of those reports, the risk associated with such procedures seems justified in view of an improved prognosis.…”

Section: Introductionmentioning

confidence: 99%

Results of optimal debulking surgery with bowel resection in patients with advanced ovarian cancer

et al. 2016

View full text Add to dashboard Cite

BackgroundThe surgical treatment of patients with advanced-stage ovarian cancer is based on maximal cytoreduction with widening the debulking on the extra-ovarian tissues and infiltrated organs. The purpose of the study was to assess the outcome after optimal cytoreduction with partial bowel resection and to find the risk factors of relapse. Another goal was the quantitative and qualitative assessment of intra- and postoperative complications in the studied group.MethodsThe analysis of debulking procedures with intestinal resection and postoperative period in 33 ovarian cancer patients, The International Federation of Gynecology and Obstetrics (FIGO) stages III and IV, was performed.ResultsThe optimal cytoreduction defined as less than 1.0 cm residual disease was achieved in all patients including the following: 26 patients (78.8 %) with no macroscopic residual disease, 4 patients (12.1 %) with the largest residual tumor less than 0.5, and 3 patients (9.1 %) with 0.5 cm to less than 1.0 cm residual disease. The rectosigmoid resection was the most common surgical procedure (n = 27). The risk of relapse was significantly higher in subjects who had the macroscopic residual tumor left during the primary operation (57.1 vs. 11.5 %, P = 0.035). A primary bowel tumor size was another predictor of relapse. The maximum tumor diameter was significantly larger (14.9 ± 6.7 cm vs. 10.3 ± 4.7 cm, P = 0.047) in patients who developed the relapse.ConclusionsAs presented in the article, our outcomes and other authors’ observations indicate that debulking surgery with bowel resection in patients with advanced ovarian cancer brings good results. Complications connected with bowel surgery are to be accepted. The interesting thing is that a primary bowel tumor size was a predictor of relapse.

show abstract

“…Studies have reported that radical pelvic resection (i.e., radical oophorectomy, en bloc rectosigmoid colectomy, or modified posterior pelvic exenteration) is feasible and effective to completely remove pan-pelvic disease without significant morbidity [22,23] . Extensive bowel resections are also performed as part of cytoreductive procedures [24][25][26] . Salani et al reported that multiple (≥2) bowel resections were necessary in order to obtain an optimal or complete RD in ASOC [27] .…”

Section: Reasons Conditionsmentioning

confidence: 99%

Digestive resections in advanced-stage ovarian cancer

Bacalbaşa

Ionescu²,

Ionescu

et al. 2016

Adv Mod Oncol Res

View full text Add to dashboard Cite

Abstract:The standard frontline treatment for advanced-stage ovarian cancer (ASOC) consists of maximal cytoreduction surgery associated with platinum/paclitaxel-based chemotherapy. Several studies have proven that patients with no gross residual disease (RD) have better survival rates than those with optimal but visible RD (RD ≤1 cm). In order to achieve this, more radical cytoreductive procedures such as radical pelvic resection and extensive upper abdominal procedures are performed. However, some investigators have suggested that, although effective, radical surgery cannot fully compensate tumor biology, which is a major determinant in survival and in turn influences the likelihood of surgical cytoreduction. The aim of this review was to present the procedures defining ultra-radical (extensive) surgery and to evaluate its feasibility and morbidity in the management of ASOC.Keywords: ovarian cancer; residual disease; cytoreductive surgery

show abstract

The evaluation of intra- and postoperative complications related to debulking surgery with bowel resection in patients with FIGO stage III–IV ovarian cancer

Cited by 13 publications

References 9 publications

Evaluation of intraoperative and postoperative complications related to lymphadenectomy in ovarian cancer patients

Evaluation of intraoperative and postoperative complications related to lymphadenectomy in ovarian cancer patients

Results of optimal debulking surgery with bowel resection in patients with advanced ovarian cancer

Digestive resections in advanced-stage ovarian cancer

Contact Info

Product

Resources

About