The European Society for Blood and Marrow Transplantation (EBMT) roadmap and perspectives to improve nutritional care in patients undergoing hematopoietic stem cell transplantation on behalf of the Cellular Therapy and Immunobiology Working Party (CTIWP) and the Nurses Group (NG) of the EBMT

Casirati, Amanda; Salcedo, Isabel; Cereda, Emanuele; Chabannon, Christian; Ruggeri, Annalisa; Kuball, Jürgen; Clout, Ruth; Mooyaart, Jarl E.; Kenyon, Michelle; Caccialanza, Riccardo; Pedrazzoli, Paolo; Kisch, Annika

doi:10.1038/s41409-023-02018-z

Cited by 5 publications

(19 citation statements)

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“…In all patients eligible for HSCT, the clinical guidelines of the European Society for Parenteral and Enteral Nutrition (ESPEN) recommend the systematic and comprehensive monitoring of nutritional status before, during and after transplant, together with an adequate nutritional support, when required ( 19 , 20 ). Literature shows that between 10 and 15% of patients have malnutrition prior to transplant ( 6 ).…”

Section: Nutritional Screening and Support During Hsct Proceduresmentioning

confidence: 99%

“…For this reason, before HSCT admission, all patients must receive a nutritional assessment and screening in order to implement corrective measures as soon as possible ( 6 ). There are different tools to assess the nutritional status of the patients and detect the risk of malnutrition, but currently one of the most used is the Malnutrition Universal Screening Tool (MUST).…”

Section: Nutritional Screening and Support During Hsct Proceduresmentioning

confidence: 99%

“…The conditioning regimen administered before HSCT generally causes inflammatory damage to the gastrointestinal tract, which determines the disruption of the mucosal barrier, leading to mucositis, loss of appetite, diarrhea, nausea, vomiting and dysgeusia ( 6 ). These symptoms, together with the catabolic state and infections sequelae, often result in suboptimal nutritional intake followed by loss of weight and lean body mass before and after transplant ( 7 ).…”

Section: Introductionmentioning

confidence: 99%

“…The nutritional status deeply impacts on hospitalization, quality of life, infection rate and survival after HSCT ( 10–12 ). Moreover, in the allogeneic setting, nutritional impairment and gastroenteric damage may also trigger intestinal graft-versus-host disease (GvHD), which can further negatively affect food intake and gut absorption ( 6 ). It is crucial to consider that these alterations tend to persist long after transplant, having reported that 50% of the patients have not regained their weight after a year from HSCT, a fact that makes even more relevant the need to monitor the nutritional status of our patients before, during and after the procedure ( 13 ).…”

Section: Introductionmentioning

confidence: 99%

“…Even if all these implications are widely studied, in real-world clinical practice, both awareness and consideration of nutritional issues remain poor and nutritional assessment is not routinely performed ( 6 ).…”

Section: Introductionmentioning

confidence: 99%

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Nutritional aspects in autoimmune diseases undergoing hematopoietic stem cell transplantation: overview and recommendations on behalf of the EBMT ADWP and Nurses Group

Gandossi,

Jessop,

Hahn

et al. 2024

Front. Nutr.

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Autoimmune diseases (ADs) represent a heterogeneous group of conditions affecting 5–10% of the global population. In recent decades, hematopoietic stem cell transplant (HSCT), mainly autologous, has been successfully adopted to treat patients affected by severe/refractory ADs. In this context malnutrition has a detrimental impact on relapse, mortality, infection rate, engraftment, long-term survival, and prolongation of hospitalization. However, in this population, the management of nutrition should be improved since nutritional assessment is partially performed in routine clinical practice. A panel of nurses and physicians from the European Society for Blood and Marrow Transplantation (EBMT) reviewed all available evidence based on current literature and expert practices from centers with extensive experience in HSCT for ADs, on the nutritional management of ADs patients during HSCT procedure. In this context, adequate nutritional status predicts a better response to treatment and improves quality of life. Herein, a systematic and comprehensive monitoring of nutritional status before, during and after HSCT, with adequate nutritional support in the case of ADs patients, in addition to assessing the dietary requirements associated with HSCT has been covered. Moreover, given the singularity of each AD, the underlying disease should be considered for an appropriate approach. The management and evaluation of nutritional status must be carried out by a multidisciplinary team to assess the needs, monitor the effectiveness of each intervention, and prevent complications, especially in complex situations as patients affected by ADs.

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Section: Nutritional Screening and Support During Hsct Proceduresmentioning

confidence: 99%

Section: Nutritional Screening and Support During Hsct Proceduresmentioning

confidence: 99%