The European Respiratory Journal makes COPD a priority

Soriano, Joan B.; Brusasco, Vito; Dinh-Xuan, Anh Tuan

doi:10.1183/09031936.00055711

Cited by 14 publications

(8 citation statements)

References 9 publications

(8 reference statements)

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“…Exacerbations of chronic obstructive pulmonary disease (COPD) are defined as acute events characterised by a worsening of the patient's respiratory symptoms, particularly dyspnoea, beyond day-to-day variation, leading to a change in medical treatment and/or hospitalisation [1,2]. Exacerbations of COPD are a leading cause of hospitalisation and healthcare expenditures, particularly in frail, elderly patients.…”

Section: To the Editormentioning

confidence: 99%

“…Exacerbations of COPD are a leading cause of hospitalisation and healthcare expenditures, particularly in frail, elderly patients. They alter the health-related quality of life and the natural course of disease, increasing the risk of mortality, both during and after the acute event [1,2]. Patients with COPD frequently have chronic comorbidities [1].…”

Section: To the Editormentioning

confidence: 99%

“…The majority of patients with invasive aspergillosis are critically ill, requiring intensive care unit (ICU) admission. The presence of Aspergillus in the airways of critically ill patients carries higher mortality risk [2], and should prompt further diagnostic evaluation, including fibreoptic bronchoscopy [3].…”

Section: To the Editormentioning

confidence: 99%

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Exacerbation of respiratory symptoms in COPD patients may not be exacerbations of COPD

et al. 2013

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Section: To the Editormentioning

confidence: 99%

Section: To the Editormentioning

confidence: 99%

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Exacerbation of respiratory symptoms in COPD patients may not be exacerbations of COPD

et al. 2013

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“…Original respiratory science and medicine will remain our priority [9][10][11][12][13]. We will launch new sections in the coming few months in order to challenge our environment.…”

Section: New Sectionsmentioning

confidence: 99%

The ambition of the European Respiratory Journal

Humbert

2012

European Respiratory Journal

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“…Theirs is a friendly addition, given that the LLN versus fixed ratio debate appears to be more heated than ever. Within the ERJ, it is welcome that forthcoming authors report both outcomes [8]. Thus, eventually, meta-analyses based on individual patient data will help to investigate further this question and identify the more accurate of these two approaches.…”

mentioning

confidence: 99%

Ageing lungs and very elderly COPD: anytime and anywhere

Soriano

Suissa

2016

Eur Respir J

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@ERSpublicationsWithin the current epidemiological transition, expect and find incident COPD cases anytime, anywhere http://ow.ly/UOccWThe recent European Respiratory Society/American Thoracic Society Task Force for COPD Research statement [1] requested new studies that "…evaluate the impact of age on the importance of identifying an airflow limitation (i.e. is it more important to identify asymptomatic airflow limitation in a 30-year-old than an 80-year-old?)", as well as those studies that compare outcomes among individuals diagnosed with chronic obstructive pulmonary disease (COPD) on the basis of the fixed ratio versus lower limit of normal (LLN) thresholds. In this issue of the European Respiratory Journal (ERJ), LUOTO et al. [2] report the results of a study that fulfils both goals.The world's population is ageing at a prodigious rate and it is anticipated the life span of newborns in the year 2000 in many Western countries might reach 100 years [3]. Ergo, the frequency of noncommunicable diseases will increase exponentially, and COPD, intrinsically associated with ageing and tobacco use/ exposure, is also expected to increase its burden, as many more people will live with it for longer. The recent Global Burden of Disease update estimated the number of people worldwide with COPD to be 328 million [4]. However, given the likely ecological fallacy [5], for a universally very high level of underdiagnosis [6], there are many questions that remain unanswered relating to the elderly with COPD. A research call for COPD in the elderly, similar to that for asthma in the elderly, is needed [7].As reviewed by LUOTO et al. [2], there were few studies quantifying the incidence of spirometrically confirmed COPD in the literature, particularly within the elderly. As exemplified in their table 5, there is a wide heterogeneity in the published estimates of incidence, varying by method, location, age and sex. Theirs is a friendly addition, given that the LLN versus fixed ratio debate appears to be more heated than ever. Within the ERJ, it is welcome that forthcoming authors report both outcomes [8]. Thus, eventually, meta-analyses based on individual patient data will help to investigate further this question and identify the more accurate of these two approaches.LUOTO et al.[2] followed for 6 years nearly a thousand individuals aged 65-100 years who had an acceptable spirometry at baseline. They participated in the longitudinal Good Aging in Skåne study, which in turn is part of the Swedish National Study on Aging and Care. Not surprisingly for an elderly population, the incidence of airflow limitation compatible with COPD was higher according to the fixed ratio definition of a forced expiratory volume in 1 s/(forced) vital capacity ratio <0.7 than with the LLN definition, as the fixed ratio underestimates airflow limitation in the young, while it is overestimated in the elderly.This type of descriptive epidemiology research could be considered simple but even such simple studies do face complex methodological challenges...

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The European Respiratory Journal makes COPD a priority

Cited by 14 publications

References 9 publications

Exacerbation of respiratory symptoms in COPD patients may not be exacerbations of COPD

Exacerbation of respiratory symptoms in COPD patients may not be exacerbations of COPD

The ambition of the European Respiratory Journal

Ageing lungs and very elderly COPD: anytime and anywhere

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