The ethnobotanical, phytochemistry and pharmacological activities of Psidium guajava L.

Ugbogu, Eziuche Amadike; Emmanuel, Okezie; Uche, Miracle Ebubechi; Dike, Emmanuel Dike; Okoro, Benedict Chukwuebuka; Ibe, Chibuike; Ude, Victor Chibueze; Ekweogu, C.N.; Ugbogu, Ositadinma Chinyere

doi:10.1016/j.arabjc.2022.103759

Cited by 19 publications

(5 citation statements)

References 160 publications

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“…Psidium guajava (L.) is a tropical food plant belonging to the Myrtaceae family, widely used in the traditional medicine for the treatment of various diseases such as diarrhea, diabetes, rheumatism, ulcers, malaria, cough, and bacterial infections [51]. Different parts (leaves, stems, barks, roots, and fruits) of P. guajava have a unique application in different parts of the world.…”

Section: Psidium Guajavamentioning

confidence: 99%

“…The leaves have been used in Guamanian folk medicine as a traditional herbal remedy for bladder infections, a vaginal douche, cleansing wounds, skin rashes, gastroenteritis, and back pain [2,7]. Ugbogu et al [51] listed multiple bioactive compounds found in the leaves of P. guajava, including gallic acid, pedunculagin, casuariin, prodelphinidin, catechin, chlorogenic acid, rutin, vanillic acid, quercetin, p-hydroxyl benzoic acid, syringic acid, kaempferol, apigenin, cinnamic acid, luteolin, reynoutrina, morin, ellagic acid, guavinoside B, myrciaphenone B, vescalagin, castalagin isomer, hyperoside, guaijaverin, ursolic acid, oleanolic acid, methyl gallate, procyanidin. These bioactive compounds exhibited different pharmacological properties such as antidiabetic, anti-inflammatory, antioxidant, antifungal, antibacterial, neuroprotective, cardioprotective, and anticancer activities.…”

Section: Psidium Guajavamentioning

confidence: 99%

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Ethnobotanical Review of Selected Medicinal Plants in Guam for the Treatment of Urinary Tract Ailments and Their Pharmacological Properties

Ferdosh

2023

Sci. Pharm.

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The Chamorro healers of Guam have more than a thousand years of history of using herbs and medicinal plants for the treatment of common ailments. The objective of this study is to review the bioactive compounds and pharmacological properties of medicinal plants which are used for urinary tract health by local healers. Literature searches were performed using Google Scholar, ScienceDirect, PubMed, and SpringerLink, by using several keywords, including “medicinal plants in Guam”, “traditional uses”, “bioactive compounds”, “pharmacological properties”, and “urinary tract infections”. This review highlights the traditional uses, bioactive compounds, and pharmacological properties of five medicinal plant species, namely Euphorbia hirta, Phyllanthus amarus, Premna serratifolia, Psidium guajava, and Urena lobata. Phenolics, alkaloids, terpenoids, essential oils, and polypeptides are the leading secondary metabolites reported in different plant extracts, which have been found to have significant antimicrobial, antioxidant, anti-inflammatory, antidiabetic, and anticancer properties. The therapeutic claims made about medicinal plants in Guam are well supported by the literature, having similar applications and pharmacological properties in other regions of the world. These medicinal plants have a lot of unexplored potential that might be utilized to develop more potent drugs for the treatment of infectious diseases, as well as food and herbal supplements.

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Section: Psidium Guajavamentioning

confidence: 99%

Section: Psidium Guajavamentioning

confidence: 99%

Ethnobotanical Review of Selected Medicinal Plants in Guam for the Treatment of Urinary Tract Ailments and Their Pharmacological Properties

Ferdosh

2023

Sci. Pharm.

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“…The guava is predominantly known for its antihyperglycemic activity and the leaf and bark extracts of this plant are used by ethnic people traditionally from the regions of South Africa, Indonesia, Madagascar, etc. to treat diabetes in different medicinal formulations such as raw juice, decoctions, and infusions [37]. It was reported that the flavonoid compounds and polysaccharides existing in the guava leaves are regarded as the responsible constituents for their promising hypoglycemic activity by inhibiting the activity of αamylase and α-glucosidase enzymes [1].…”

Section: In Vitro Biological Studies Of Guava Leaf Extracts 221 Enzym...mentioning

confidence: 99%

Nutritional Composition, Mineral Profiling, In Vitro Antioxidant, Antibacterial and Enzyme Inhibitory Properties of Selected Indian Guava Cultivars Leaf Extract

Sam Arul Raj,

Amalraj,

Alarifi

et al. 2023

Pharmaceuticals

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Psidium guajava L. is a small evergreen tree known for its magnificent medicinal and nutritional value. This study aimed to evaluate the nutritional profile and in vitro pharmacological potentialities of the different leaf extracts of four cultivars of Psidium guajava namely Surka chitti, Allahabad safeda, Karela, and Lucknow-49. The standard procedures of the Association of Official Analytical Chemists (AOAC) were followed to carry out the nutritional analysis and all of the cultivars recorded the presence of elements at a nominal range. The highest presence of phenols (125.77 mg GAE/g) and flavonoids (92.38 mg QE/g) in the methanolic leaf extract of the Karela cultivar was recorded. A wide range of minerals such as sodium, phosphorus, magnesium, zinc, and boron were recorded with a higher percentage in the Karela cultivar of Psidium guajava. In the enzyme inhibitory assays, Allahabad safeda showed potential inhibition with an IC50 of 113.31 ± 1.07, 98.2 ± 0.66 and 95.73 ± 0.39 μg/mL in α-amylase, α-glucosidase, and tyrosinase inhibition assays, respectively. The strong antioxidant effect was established by Lucknow-49 (IC50 of 74.43 ± 1.86 μg/mL) and Allahabad safeda (IC50 of 78.93 ± 0.46 μg/mL) for ABTS and DPPH assays, respectively. The ethyl acetate and methanolic leaf extracts of the Allahabad safeda cultivar showed better inhibition against Pseudomonas aeruginosa with an MIC of 14.84 and 28.69 µg/mL, respectively. A decent mean zone of inhibition was recorded in methanolic leaf extract that ranged from 21–25 mm in diameter against the tested bacterial strains (Proteus vulgaris, Bacillus subtilis, and P. aeruginosa). This is the first scientific report on the comparative and comprehensive analysis of indigenous guava cultivars to evidently shortlist the elite cultivars with enriched dietary nutrition and biological activities.

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“…Worldwide, more than 50,000 plant species are documented for their clinical benefits and pharmacological effects on humans and domestic animals (Sharma et al 2022). Studies show that 80% of the world's population uses medicinal plants or their bioactive compounds for the prevention, cure or treatment of several diseases (Macía et al 2005;Ajibesin et al 2012;Chiribagula et al 2020;Mlilo and Sibanda 2022;Ugbogu et al 2022;Delices et al 2023). In developing countries, the use of herbal medicines as an alternative to modern medicine is very common (Nath and Puzari 2022).…”

Section: Introductionmentioning

confidence: 99%

Ethnobotanical knowledge of Prunus africana (Hook. f.) Kalkman (Rosaceae) by people living in community forests in North Kivu, Eastern Democratic Republic of Congo

Muhesi,

Betti,

Din

et al. 2023

Ethnobot. Res. App.

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Background: Prunus africana (Hook. f) Kalkman (Rosaceae) is a multi-purpose species with important utility value for the populations that depend on it. Indeed, local populations living in community forests use P. africana. The objective of this study is to document the different uses of P. africana by local populations in traditional medicine for a better vulgarization for a sustainable management of the resource.Methods: Ethnobotanical surveys were conducted in four P. africana distribution areas in North Kivu. Data were collected on the basis of a survey from 221 informants. Statistical analysis and calculation of ethnobotanical indices were performed using R 4.1.2 software.Results: Results of the investigations show that P. africana is by far used in medical practices (96.83%). It is also used as wood energy (60.18 %), charcoal (40.27 %), in handicrafts (7.24 %), construction (6.79 %), food (2.26 %) and traditional rites (0.45 %). In traditional pharmacopoeia, the characterization of the uses allowed us to identify 23 diseases for which P. africana extracts are used to treat them. The bark and leaves are the most used organs in the recipes. The decoction (99.5%), the macerated (10.41%) and the powders (7.69%) are the galenic or pharmaceutical forms in which the local populations prepare the remedies. The potions prepared are mainly administered orally (99.5%). Conclusion:The multiple forms of use of P. africana by the populations of North Kivu, both in medicine and in other categories of use, constitute a threat to its survival. For a sustainable management, the results of this study reveal that it is possible to substitute the species P. africana with other plant species with similar potential in order to limit its overexploitation.

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The ethnobotanical, phytochemistry and pharmacological activities of Psidium guajava L.

Cited by 19 publications

References 160 publications

Ethnobotanical Review of Selected Medicinal Plants in Guam for the Treatment of Urinary Tract Ailments and Their Pharmacological Properties

Ethnobotanical Review of Selected Medicinal Plants in Guam for the Treatment of Urinary Tract Ailments and Their Pharmacological Properties

Nutritional Composition, Mineral Profiling, In Vitro Antioxidant, Antibacterial and Enzyme Inhibitory Properties of Selected Indian Guava Cultivars Leaf Extract

Ethnobotanical knowledge of Prunus africana (Hook. f.) Kalkman (Rosaceae) by people living in community forests in North Kivu, Eastern Democratic Republic of Congo

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