The estimation of oxygen consumption

Lafarge, C. G.; Miettinen, Olli S.

doi:10.1093/cvr/4.1.23

Cited by 378 publications

(219 citation statements)

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“…In the remaining cases, including patients receiving positive pressure ventilation, oxygen consumption was assumed from previously published norms. 15 Cardiac output was determined by the Fick principle and was then divided by body surface area to determine cardiac index. PVR was determined using Ohm's law and was indexed to body surface area (PVRI) by using cardiac index in the calculation.…”

Section: Methodsmentioning

confidence: 99%

Safety of Cardiac Catheterization at a Center Specializing in the Care of Patients with Pulmonary Arterial Hypertension

et al. 2013

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Cardiac catheterization is important for the management of patients with pulmonary arterial hypertension (PAH). It is used for diagnosis, assessment, and monitoring of PAH patients, as well as to perform interventions such as balloon atrial septostomy and coil embolization of collateral vessels. Although reports on the risks of catheterization in PAH patients are scarce, many centers hesitate to perform these procedures in such fragile patients. We performed a retrospective chart review of all cardiac catheterizations performed in PAH patients over 10 years at our pulmonary hypertension center. Demographic, hemodynamic, and outcome data were collected. Complication rates were determined, and multivariate proportional hazards modeling was performed to identify predictors of catheterization-related complications. There were 1,637 catheterizations performed in 607 patients over 10 years. Pediatric patients accounted for 50% of these cases, 48% were performed in patients with idiopathic PAH, and 49% were performed under general anesthesia. While the overall complication rate was 5.7%, the rate of major complications was only 1.2% (n = 20). Although there were 8 deaths during the admission following catheterization, only 4 of these were related to the procedure, yielding a catheterization-related mortality of 0.2%. In conclusion, when performed at a pulmonary hypertension center with expertise in the care of PAH patients, cardiac catheterization is associated with low complication rates and mortality, and it should remain an important tool in the management of these patients.

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Section: Methodsmentioning

confidence: 99%

Safety of Cardiac Catheterization at a Center Specializing in the Care of Patients with Pulmonary Arterial Hypertension

et al. 2013

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“…Calculations for Qp:Qs were performed using the Fick principle and an assumed oxygen consumption of 180 mL/min · m 2 . 2 To compare pulmonary artery growth between groups, a ratio was obtained by dividing the sum of the diameters of the right and left pulmonary arteries by the diameter of the descending aorta at the level of the diaphragm in systole. 3 Coronary perfusion pressure was obtained by subtracting the mean right atrial pressure from the aortic diastolic pressure.…”

Section: Methodsmentioning

confidence: 99%

Hemodynamic Profile After the Norwood Procedure With Right Ventricle to Pulmonary Artery Conduit

Maher¹,

Pizarro²,

Gidding³

et al. 2003

Circulation

103

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Background-The balance of systemic, pulmonary, and coronary blood flow after the Norwood operation for hypoplastic left heart syndrome (HLHS) is critical to early survival. We hypothesized that a right ventricle to pulmonary artery conduit (instead of a systemic to pulmonary artery shunt) would result in hemodynamic changes consistent with a more stable balance of systemic, pulmonary, and coronary perfusion. Methods and Results-Hemodynamic data were obtained during cardiac catheterization before the hemi-Fontan procedure from 24 patients with HLHS; the first 10 had a Norwood operation with a systemic to pulmonary artery shunt, and the latter 14 had the Norwood operation with a right ventricle to pulmonary artery conduit. Significant differences were present, with the right ventricle to pulmonary artery conduit group having a higher aortic diastolic pressure (55 versus 42 mm Hg), a narrowed systemic pulse pressure (43 versus 64 mm Hg), a lower Qp:Qs (0.92 versus 1.42), a higher coronary perfusion pressure (46 versus 32 mm Hg), and a higher ratio of pulmonary artery diameter to descending aorta diameter (1.51 versus 1.37). Conclusions-We conclude that, in HLHS after the Norwood operation, the right ventricle to pulmonary artery conduit modification produces hemodynamic changes consistent with improved coronary perfusion and a more favorable distribution of systemic, pulmonary, and coronary blood flow.

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“…Similarly, the formula suggested for the estimation of 0 2 consumption during catheterization (LaFarge and Miettinen, 1970) is based almost entirely on a pediatric population. In short, despite the need to estimate 0 2 consumption in the adult catheterization laboratory on occasion, standard values for this variable, and the extent G. J. Dehmer et al: Oxygen consumption in adults 437 of its variability among adult patients, are unknown.…”

Section: Introductionmentioning

confidence: 99%

Oxygen consumption in adult patients during cardiac catheterization

Dehmer

Firth

Hillis

1982

Clinical Cardiology

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Summary:The determination of cardiac output by the Fick principle requires the quantitation of the arteriovenous oxygen (02) content difference across the pulmonary bed and the 0 2 consumption. Since a correct measurement of 0 2 consumption may be difficult, an assumed value is sometimes substituted into this equation. Despite this practice, there is no appropriate reference standard for 0 2 consumption applicable to the adult catheterization laboratory. Therefore, we determined 0 2 consumption in 108 patients (69 men and 39 women, mean age, 49 years) at the time of catheterization by multiplying the arteriovenous 0 2 content difference by the indicator dilution cardiac output, thereby eliminating errors related to the collection and analysis of a timed collection of expired air. 0 2 consumption index (02 consumption/m2 of body surface area) averaged 126f26 ml/min/m2 (meanfSD), but there was wide variability (65-250 ml/min/m2). 0 2 consumption was not affected by patient age or sex but was lower in those who were mildly sedated before catheterization (sedated, 121 f 2 2 ml/min/m2; nonsedated, 132f28 ml/min/m2; p = 0.023). Thus, 0 2 consumption varies greatly among adults at the time of cardiac catheterization, so that any attempt at estimating this variable is fraught with major potential error.

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The estimation of oxygen consumption

Cited by 378 publications

References 0 publications

Safety of Cardiac Catheterization at a Center Specializing in the Care of Patients with Pulmonary Arterial Hypertension

Safety of Cardiac Catheterization at a Center Specializing in the Care of Patients with Pulmonary Arterial Hypertension

Hemodynamic Profile After the Norwood Procedure With Right Ventricle to Pulmonary Artery Conduit

Oxygen consumption in adult patients during cardiac catheterization

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