The essential role of adenine nucleotide translocase 4 on male reproductive function in mice
Fengyuan Yang,
Xiali Yang,
Hui Zhu
et al.
Abstract:Adenine nucleotide translocator 4 (
Ant4
), an ATP/ADP transporter expressed in the early phases of spermatogenesis, plays a crucial role in male fertility. While
Ant4
loss causes early arrest of meiosis and increased apoptosis of spermatogenic cells in male mice, its other potential functions in male fertility remain unexplored. Here, we utilized
Ant4
knockout mice to delineate the effects of
Ant4
-deficiency on male r… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.