Phonocardiography, a diagnostic procedure introduced by Einthoven "in 1894, was employed by Counihan et al.(1) to determine the cause of the initial vibrations of the first heart sound. These low frequency, low amplitude vibrations are commonly thought to be due to atrial systole. The authors observed that these initial vibrations appeared, however, even though the atria were fibrillating and even though atrial and ventricular sys" tole were widely separated because of heart block. These data suggested that the initial vibrations might be caused by the onset of ventricular contraction through mechanisms unrelated to atrial contrac:tion, the movement of the heart in the chest, or the taking up of slack in the chordae tendineae and atrioventric ular valves before closure. Phonocardiography was also employed by Ravin & Darley (2) for the study of apical diastolic murmurs which occurred in certain patients with patent ductus arteriosus. The murmurs were similar to the mid-diastolic rumble of mitral stenosis, being low-pitched, located at the cardiac apex, and best heard with the patient in the left lateral decubitus position after exercise. The presence of these murmurs was explained by: (a) enlargement of the left ventricle causing a relative narrowing of the mitral orifice, (b) a large volume of blood traversing the mitral valve at a high rate of flow, or (c) a thin chest wall which makes blood turbulence more a udible. Cardiac catheterization has been widely employed during the past year, particularly in the field of acquired heart disease, and techniques have been improved with the development of recording instruments of high fidelity. Ellis, Gauer & Wood (3) supplied a method for recording pressure tracings by means of a miniature intracardiac manometer. Excellent illustra tions of artifact-free pulse waves from within the heart and great vessels of humans and dogs were illustrated. Helmsworth et al. (4) visualized the coronary arteries during life by retrograde catheterization of the carotid and brachial arteries in five patients. Small polyethylene or woven catheters were inserted into the ascending aorta; Diodrast (iodopyracet) or Neo Iopax (sodium iodomethamate) was forcibly injected and serial roentgeno grams were taken. The large and small branches of the coronary arteries were demonstrated among normal subjects, and failure of the coronary vessels to fill after ligation was demonstrated in 10 dogs.