2004
DOI: 10.1186/1550-2783-1-2-35
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The Ergogenic Potential of Arginine

Abstract: Arginine is a conditionally essential amino acid that is involved in protein synthesis, the detoxification of ammonia, and its conversion to glucose as well as being catabolized to produce energy. In addition to these physiological functions, arginine has been purported to have ergogenic potential. Athletes have taken arginine for three main reasons: 1) its role in the secretion of endogenous growth hormone; 2) its involvement in the synthesis of creatine; 3) its role in augmenting nitric oxide. These aspects … Show more

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Cited by 61 publications
(46 citation statements)
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“…21 It has multiple pharmacologic properties (antioxidant, anti-inflammatory, antihypercholesterolemic, muscle relaxant, immunomodulatory, and so forth). 12 These widespread activities could be a result of its effect on various metabolizing enzymes and their final metabolites.…”
Section: Discussionmentioning
confidence: 99%
“…21 It has multiple pharmacologic properties (antioxidant, anti-inflammatory, antihypercholesterolemic, muscle relaxant, immunomodulatory, and so forth). 12 These widespread activities could be a result of its effect on various metabolizing enzymes and their final metabolites.…”
Section: Discussionmentioning
confidence: 99%
“…This may be because arginine stimulates the secretion of the growth hormone. Campbell et al (2004) reported that it is well documented that the infusion of arginine stimulates growth hormone secretion from the anterior pituitary. This increase in growth hormone secretion has been attributed to the suppression of endogenous somatostatin secretion (Alba-Roth et al, 1988).…”
Section: Resultsmentioning
confidence: 99%
“…For instance, it has been shown that restricted blood flow is an important determinant of performance in speed skaters [10]. However, information remains scarce regarding the impact of nutritional products on performance via their impact on vascular function, endothelial function and blood flow [11]. It is also not clear how dietary intake of polyphenols affects endothelial function in athletes, as most studies that have investigated this topic have been conducted in non-athletes as well as patients with chronic disease.…”
Section: Introductionmentioning
confidence: 91%