Abstract:Mesial Temporal Lobe Epilepsy (MTLE) is the most common symptomatic focal epilepsy, with hippocampal sclerosis (HS) representing the most commonly occurring pathology linked to MTLE.In the past HS has been understood to represent a focal neuropathological alteration linked to the generation of seizures (i.e., the epileptic focus). However, the phenomenon that not all patients become seizure-free after surgical resection of the hippocampus has given rise to the concept that seizures and interictal epileptiform … Show more
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