The epidemiology of transverse myelitis

Bhat, Anupama; Naguwa, Stanley M.; Cheema, Gurtej S.; Gershwin, M. Eric

doi:10.1016/j.autrev.2009.12.007

Cited by 142 publications

(107 citation statements)

References 57 publications

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“…Our patient does not meet the criteria proposed by Wingerchuk et al 17 since no optic nerve inflammation was detected, yet other symptoms of central nervous system affection were shown, such as meningeal syndrome and confusion, which are not typical for neuromyelitis optica. The other possible causes of myelitis 18 were excluded during the diagnosis (i.e. infectious background) or due to irrelevant history (vaccinations or parasites).…”

Section: Discussionmentioning

confidence: 99%

Longitudinal Myelitis as a Rare First Symptom of Lupus in Overlap Syndrome

Wilczek-Paradowska¹,

Paradowski

2015

Arch Rheumatol

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Section: Discussionmentioning

confidence: 99%

Longitudinal Myelitis as a Rare First Symptom of Lupus in Overlap Syndrome

Wilczek-Paradowska¹,

Paradowski

2015

Arch Rheumatol

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“…Demyelinating disorders, such as MS and NMO, are probably the most common causes of ATM. Absent MS and NMO, most cases of ATM appear to follow an infection or vaccination, although the etiology of ATM is not determined in up to 30% of cases [77]. Rarely, systemic autoimmune disorders, such as systemic lupus erythematosis (SLE) and Sjögren's Syndrome can affect the spinal cord [77].…”

Section: Acute Transverse Myelitismentioning

confidence: 99%

“…Absent MS and NMO, most cases of ATM appear to follow an infection or vaccination, although the etiology of ATM is not determined in up to 30% of cases [77]. Rarely, systemic autoimmune disorders, such as systemic lupus erythematosis (SLE) and Sjögren's Syndrome can affect the spinal cord [77]. The reported incidence of ATM depends on whether or not patients with MS and NMO are included in the estimate.…”

Section: Acute Transverse Myelitismentioning

confidence: 99%

“…The reported incidence of ATM depends on whether or not patients with MS and NMO are included in the estimate. Overall, there are approximately 25 cases of ATM per million of the population each year; if patients with MS and NMO are excluded, the annual incidence of ATM is somewhere between 1 and 8 per million, with a peak incidence between the ages of 10 and 19 and 30 and 39 [77][78][79].…”

Section: Acute Transverse Myelitismentioning

confidence: 99%

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Immune Mediated Diseases and Immune Modulation in the Neurocritical Care Unit

Geldern¹,

McPharlin

Becker

2012

Neurotherapeutics

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This chapter will review the spectrum of immunemediated diseases that affect the nervous system and may result in an admission to the neurological intensive care unit. Immunomodulatory strategies to treat acute exacerbations of neurological diseases caused by aberrant immune responses are discussed, but strategies for long-term immunosuppression are not presented. The recommendations for therapeutic intervention are based on a synthesis of the literature, and include recommendations by the Cochrane Collaborative, the American Academy of Neurology, and other key organizations. References from recent publications are provided for the disorders and therapies in which randomized clinical trials and large evidenced-based reviews do not exist. The chapter concludes with a brief review of the mechanisms of action, dosing, and side effects of commonly used immunosuppressive strategies in the neurocritical care unit.

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“…The mechanism of action of the vaccines is to stimulate the immune system. However this process carries the risk of developing rare neurological adverse reactions associated with vaccination (1)(2)(3)(4).…”

Section: Introductionmentioning

confidence: 99%

Difteri Tetanoz Toksoid aşısından (Td) sonra gelişen transvers myelit: Olgu sunumu

Savaş¹,

Akçam²,

Çiçek³

et al. 2013

Tftr

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Turk J Phys Med Re hab 2013;59:349-52 Türk Fiz T›p Re hab Derg 2013;59:349-52 ÖzetTransvers myelit (TM) tetanoz toksoidi içeren aşılardan sonra gelişen çok nadir bir komplikasyon olarak bildirilmiştir. Bu olgu sunumunda, erişkin tip Difteri Tetanoz Toksoid aşısı (Td) olduktan sonra kollarında ve bacaklarında progresif parestezi ve kas güçsüzlüğü gelişen kırk altı yaşında bir erkek hasta sunulmaktadır. Bu olgu literatürde Td aşısından sonra TM gelişen altıncı olgudur. Hekimler tetanoz aşısı reçete ederken bu nadir fakat ciddi yan etki konusunda uyanık olmalı; TM'in ayırıcı tanısı yapılırken aşıya bağlı gelişen TM akılda tutulmalıdır. Anah tar Ke li me ler: Tetanoz toksoid aşısı, transvers myelit, bağışıklama Sum maryTransverse myelitis (TM) has rarely been reported in association with tetanus toxoid-containing vaccines. Here, we report a 46-year-old man presented with progressive paresthesias and weakness in his arms and legs following an intramuscular injection of adult-type diphtheria and tetanus toxoids (Td). This is the sixth reported case of TM following Td vaccination. Physicians must be aware of this rare but serious side effect when prescribing Td vaccine and postvaccinial TM must be kept in mind when making a differential diagnosis of TM.

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The epidemiology of transverse myelitis

Cited by 142 publications

References 57 publications

Longitudinal Myelitis as a Rare First Symptom of Lupus in Overlap Syndrome

Longitudinal Myelitis as a Rare First Symptom of Lupus in Overlap Syndrome

Immune Mediated Diseases and Immune Modulation in the Neurocritical Care Unit

Difteri Tetanoz Toksoid aşısından (Td) sonra gelişen transvers myelit: Olgu sunumu

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