The Epidemiology of Hemolytic Uremic Syndrome: Clinical Presentation, Laboratory Findings, Management and Outcomes

Salmi, Issa Al; Shuaili, Khalfan Al; Metry, AbdelMasiah; Ismaili, Faisal Al; Hola, Alan; Hannawi, Suad

doi:10.15226/ijhbd/3/1/00119

Cited by 2 publications

(3 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It may be challenging for many doctors to diagnose HUS. Some hospitals in developing nations may lack the equipment and facilities needed for a precise diagnosis [ 8 , 26 , 33 ]. These elements might have led to an underestimation of the prevalence of HUS in most countries, for example, China.…”

Section: Reviewmentioning

confidence: 99%

“…Second, compared to rural locations, urban areas have a lower rate of STEC infection [ 23 , 24 , 31 ]. The national average hospitalization cost per patient for the same time period was 1.30 thousand US dollars; however, the average hospitalization cost for each HUS patient was 1.75 thousand US dollars, which is much higher [ 25 , 26 ]. The overall cost per patient per year was 2.15 thousand US dollars, which was also ostensibly more expensive than the country's average for urban residents' medical care expenses [ 24 , 25 ].…”

Section: Reviewmentioning

confidence: 99%

“…The overall cost per patient per year was 2.15 thousand US dollars, which was also ostensibly more expensive than the country's average for urban residents' medical care expenses [ 24 , 25 ]. In addition to supportive care, antibiotics, plasma exchange, plasma infusion, and renal replacement therapy are all used in the management of HUS [ 10 , 12 , 26 ]. The majority of these people must cover these expensive medical costs.…”

Section: Reviewmentioning

confidence: 99%

See 2 more Smart Citations

The Prevalence and Incidence of Hemolytic Uremic Syndrome: A Systematic Review

Aldharman,

Almutairi,

Alharbi

et al. 2023

Cureus

View full text Add to dashboard Cite

A hemolytic uremic syndrome is an uncommon but severe condition brought on by an overactive alternative complement system, typically involving a hereditary component. It will be crucial to comprehend the epidemiology of hemolytic uremic syndrome as research advances toward bettering its diagnosis and treatment. A systematic review was conducted to evaluate the incidence and prevalence estimates of hemolytic uremic syndrome (HUS) internationally. A thorough literature search was conducted using PubMed, Springer, Cochrane Library for Systematic Reviews, and Embase databases between 2012 and 2023 in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 recommendations. A further source of data was the PubMed Central search engine. To make sure that the evaluation included just the studies that were the most pertinent, a population, interventions, comparators, and outcomes (PICO) eligibility criterion was also used. Eight articles were included in this review. HUS had an annual crude incidence of 0.66 per 100,000 people and a standard annual incidence of 0.57 per 100,000 people. Females were more likely than males to develop HUS, but only marginally more frequently. Patients under 20 years old were the age group where HUS was most common. HUS had an average cost of $21,500 per patient, which was more expensive than the country's overall inpatient average cost for the same period. This is due to patients requiring supportive care, antibiotics, plasma exchange, plasma infusion, and renal replacement therapy, and it could take multiple courses of treatment before they improve. It was concluded that several variables, including the region, the age group affected, and the frequency of the underlying bacterial infection, determine the prevalence and incidence of HUS. HUS is often more common in children than adults and is more common in some nations. Overall, HUS is an uncommon disorder that can have significant repercussions for people who have it. For better results and fewer consequences, HUS must be diagnosed and treated as soon as possible.

show abstract

Section: Reviewmentioning

confidence: 99%