2015
DOI: 10.1093/neuonc/nou358
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The epidemiology of glioma in adults: a "state of the science" review

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Cited by 102 publications
(78 citation statements)
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“…2 The prognosis of most patients is still very poor in spite of the active surgical treatment and adjuvant therapy. 19 Current studies show that the occurrence and development of gliomas are closely related to the abnormal expression of various oncogenes and tumour suppressor genes. 19 Current studies show that the occurrence and development of gliomas are closely related to the abnormal expression of various oncogenes and tumour suppressor genes.…”
Section: Discussionsmentioning
confidence: 99%
See 1 more Smart Citation
“…2 The prognosis of most patients is still very poor in spite of the active surgical treatment and adjuvant therapy. 19 Current studies show that the occurrence and development of gliomas are closely related to the abnormal expression of various oncogenes and tumour suppressor genes. 19 Current studies show that the occurrence and development of gliomas are closely related to the abnormal expression of various oncogenes and tumour suppressor genes.…”
Section: Discussionsmentioning
confidence: 99%
“…18 Particularly, the average survival time of glioblastoma is still not more than 2 years. 19 Current studies show that the occurrence and development of gliomas are closely related to the abnormal expression of various oncogenes and tumour suppressor genes. 20 However, the precise molecular mechanism for its development is not very clear.…”
Section: Discussionsmentioning
confidence: 99%
“…All glioma samples were histologically graded in accordance with the 2007 WHO classification of tumors of the central nervous system (2). TCGA gene expression data for FER1L4 were extracted and merged with clinical outcome data for further analysis.…”
Section: Analysis Of Clinical Datamentioning
confidence: 99%
“…Patients that receive surgical treatment for this disease typically have a poor prognosis, particularly those with glioblastoma multiforme (GBM), for which the average survival time is <2 years (2). According to a previous study (3), the occurrence and progression of glioma is associated with the abnormal expression of oncogenes and tumor suppressor genes.…”
Section: Introductionmentioning
confidence: 99%
“…Human gliomas are the most prevalent malignant neoplasms of the central nervous system, with an annual incidence of ~5/100,000 worldwide (1). Despite the use of aggressive surgery in combination with chemotherapy, biological therapy and radiotherapy, gliomas continue to be therapeutically challenging (2).…”
Section: Introductionmentioning
confidence: 99%