Cutaneous Melanoma: Etiology and Therapy 2017
DOI: 10.15586/codon.cutaneousmelanoma.2017.ch2
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The Epidemiology of Cutaneous Melanoma in the White and Black African Population Groups in South Africa

Abstract: Abstract:In this chapter, two South African population groups, White and Black African, are compared with regard to cutaneous melanoma (CM). The incidence of CM in Black Africans is about 10% of that in Whites, explained at least in part by the protection offered by cutaneous melanin. The incidence has probably risen in Whites over the past 40 years but seems to be unchanged in Black Africans. The commonest CM subtype in Whites is superficial spreading; it occurs on various body sites, the most frequent being … Show more

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Cited by 11 publications
(18 citation statements)
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“…Since the black African group is the largest in SA, melanoma in this group has significant public health implications. [9] While melanoma in white individuals is most commonly of the superficial spreading histological subtype and typically affects the trunk in males and the legs in females, [9] melanoma in deeply pigmented people is more likely to be the acral lentiginous histological subtype affecting the palms and soles. [9][10][11][12] Several studies have reported worse disease outcomes for melanoma patients with darker skin types [10,12,13] and melanoma of hands and feet.…”
Section: Researchmentioning
confidence: 99%
See 3 more Smart Citations
“…Since the black African group is the largest in SA, melanoma in this group has significant public health implications. [9] While melanoma in white individuals is most commonly of the superficial spreading histological subtype and typically affects the trunk in males and the legs in females, [9] melanoma in deeply pigmented people is more likely to be the acral lentiginous histological subtype affecting the palms and soles. [9][10][11][12] Several studies have reported worse disease outcomes for melanoma patients with darker skin types [10,12,13] and melanoma of hands and feet.…”
Section: Researchmentioning
confidence: 99%
“…[9] While melanoma in white individuals is most commonly of the superficial spreading histological subtype and typically affects the trunk in males and the legs in females, [9] melanoma in deeply pigmented people is more likely to be the acral lentiginous histological subtype affecting the palms and soles. [9][10][11][12] Several studies have reported worse disease outcomes for melanoma patients with darker skin types [10,12,13] and melanoma of hands and feet. [1,14] Objectives Variation in reported SA incidence rates of melanoma [5,[7][8][9] makes it difficult to form robust conclusions.…”
Section: Researchmentioning
confidence: 99%
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“…Although data on MM incidence on the African continent remain scarce, a recent study showed the overall incidence of MM for South Africa to be 2.7 per 100 000, with the incidence in the white population being significantly higher at 23.2 per 100 000 [12]. MM in darker skin types o en presents as acral melanoma (AM), a rare distinct variant of MM that arises from the palms, soles, and nail apparatus and is associated with a poorer prognosis [13][14][15].…”
Section: Introductionmentioning
confidence: 99%