The epidemiology of blood component transfusion in Catalonia, Northeastern Spain

Bosch, Mark; Contreras, Enric; Madoz, P; Ortiz, Pilar; Pereira, Arturo; Pujol, M

doi:10.1111/j.1537-2995.2010.02785.x

Cited by 39 publications

(44 citation statements)

References 35 publications

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“…This finding contrasts with data from England and Finland where RBC use increased beginning around age 50 34,35 and where patients 70 to 80 years old had an eightfold higher RBC use than 20‐ to 40‐year‐old patients 34 . In Spain, the majority of RBCs were transfused in patients 65 years or older 7,29 and the median age for the RBC recipients in England and North Wales was 69 28 . These differences likely reflect the epidemiologic blood recipient profile across different countries and may also highlight the fact that the Central Institute is a tertiary care hospital and trauma center.…”

Section: Discussioncontrasting

confidence: 69%

“…The mean age at the time of transfusion in São Paulo was 49 years, a younger age than in developed countries where the mean age varies from 60 to 69 years old 9,10,25,28‐30 . While in developed countries 60% to 70% of the blood recipients are more than 60 years old, 7,9,28 at the HC in São Paulo, 70% of the transfused patients were less than 65 years old, with 47% being less than 45 years of age.…”

Section: Discussionmentioning

confidence: 87%

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Blood transfusion utilization and recipient survival at Hospital das Clinicas in São Paulo, Brazil

et al. 2011

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Background The characteristics of blood recipients including diagnoses associated with transfusion and post-transfusion survival are unreported in Brazil. The goals of this analysis were: 1) to describe blood utilization according to clinical diagnoses and patient characteristics at a large public hospital, Hospital das Clinicas (HC), a tertiary teaching hospital and trauma center in the city of Sao Paulo; 2) to determine the factors associated with survival of blood recipients. Methods A retrospective cross-sectional analysis was conducted on all inpatients in 2004. Data came from three sources were merged: HC electronic admission files, blood issue files, and the national death registry. The first two files consist of data about patient characteristics, clinical diagnosis, and transfusion information. Analyses comparing transfused and non-transfused patients were conducted. The third file was used to determine survival status of recipients up to three years after last transfusion. Logistic regression was conducted among transfused patients to examine survival curves and characteristics associated with follow up patient survival. Results In 2004, 30,779 patients were admitted to HC, with 3,835 (12.4%) transfused. These patients had 10,479 transfusions episodes, consisting of 39,561 transfused components; 16,748 (42%) red cells, 15,828 (40%) platelets and 6,190 (16%) plasma. The median number of components transfused was 3 (range 1 – 656) per patient admission. Mortality during hospitalization was dramatically different for patients whose admissions included transfusion or not (24% vs. 4%). After 1 year, 56% of transfusion recipients were alive. The multivariable model of factors associated with mortality following transfusion showed that the most significant factors in descending order were hospital ward, increasing age, increasing number of components transfused, and type of components received. Conclusion Ward and transfusion are markers of underlying medical conditions and are associated with the probability of survival. Platelet transfusions are common and likely reflect the types of patients treated at HC. This comprehensive blood utilization study, first of its kind in Brazil can help in developing transfusion policy analyses in South America.

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Section: Discussioncontrasting

confidence: 69%

Section: Discussionmentioning

confidence: 87%

Blood transfusion utilization and recipient survival at Hospital das Clinicas in São Paulo, Brazil

et al. 2011

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“…RBCs and FFP were preferably needed in surgical disciplines while PTL were more used in hematology/oncology. Patients with hematology/oncology treatment and cardiac/thoracic surgery did not only need the highest numbers of transfusion units but also received the most intensive hemotherapies, specified as blood products per person [12,19,23]. These findings could PBM initiative and started with first priority a retrospective status quo analysis of the flow of blood components within our institution.…”

Section: Discussionmentioning

confidence: 99%

“…Transplantation medicine, adverse effects of intensive chemotherapies, treatment of diseases with acute or chronic disturbance of the blood coagulation, and extensive operations may be some of the reasons for this difference [11,12,23]. More than the half of our transfusion-related costs are due to PTL transfusions.…”

Section: Disclosure Statementmentioning

confidence: 99%

Retrospective Analysis of the Blood Component Utilization in a University Hospital of Maximum Medical Care

Geissler

Franz²,

Buddendick³

et al. 2012

Transfus Med Hemother

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Background: Demographic data illustrate clearly that people in highly developed countries get older, and the elderly need more blood transfusions than younger patients. Additionally, special extensive therapies result in an increased consumption of blood components. Beyond that the aging of the population reduces the total number of preferably young and healthy blood donors. Therefore, Patient Blood Management will become more and more important in order to secure an increasing blood supply under fair-minded conditions. Methods: At the University Hospital of Münster (UKM) a comprehensive retrospective analysis of the utilization of all conventional blood components was performed including all medical and surgical disciplines. In parallel, a new medical reporting system was installed to provide a monthly analysis of the transfusional treatments in the whole infirmary, in every department, and in special blood-consuming cases of interest, as well. Results: The study refers to all UKM in-patient cases from 2009 to 2011. It clearly demonstrates that older patients (>60 years, 35.2–35.7% of all cases, but 49.4–52.6% of all cases with red blood cell (RBC) transfusions, 36.4–41. 6% of all cases with platelet (PTL, apheresis only) transfusions, 45.2– 48.0% of all cases with fresh frozen plasma (FFP) transfusions) need more blood products than younger patients. Male patients (54.4–63.9% of all cases with transfusions) are more susceptible to blood transfusions than female patients (36.1–45.6% of all cases with transfusions). Most blood components are used in cardiac, visceral, and orthopedic surgery (49.3–55.9% of all RBC units, 45.8–61.0% of all FFP units). When regarding medical disciplines, most transfusions are administered to hematologic and oncologic patients (12.9–17.7% of all RBC units, 9.2– 12.0% of all FFP units). The consumption of PTL in this special patient cohort (40.6–50.9% of all PTL units) is more pronounced than in all other surgical or in non-surgical disciplines. Conclusion: The results obtained from our retrospective analysis may help to further optimize the responsible and medical indication-related utilization of blood transfusions as well as the recruitment of blood donors and their timing. It may be also a helpful tool in order to avoid needless transfusions and transfusion-associated adverse events.

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“…Pemakai tertinggi adalah pasien neutropenia, agranulositosis dan sickle cell crisis. Pasien onkohematologi memakai lebih dari 70% produk trombosit dan dua pertiganya digunakan untuk profilaksis perdarahan 5,6 Berdasarkan jenis penyakitnya, pasien leukemia adalah pengguna TC terbanyak diikuti oleh sepsis dan ITP. Sejak tahun 1950, TC sudah digunakan untuk terapi suportif pada kondisi mielosupresif berat seperti pada leukemia akut maupun tumor padat.…”

Section: Pembahasanunclassified

Latar Belakang Penyakit pada Penggunaan Transfusi Komponen Darah pada Anak

Nency

Sumanti

2016

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The epidemiology of blood component transfusion in Catalonia, Northeastern Spain

Abstract: These results allow for identification of blood uses that are susceptible to improvement, help appraise the expected yield of blood safety measures, and will assist in planning the future blood supply.

Cited by 39 publications

References 35 publications

Blood transfusion utilization and recipient survival at Hospital das Clinicas in São Paulo, Brazil

Blood transfusion utilization and recipient survival at Hospital das Clinicas in São Paulo, Brazil

Retrospective Analysis of the Blood Component Utilization in a University Hospital of Maximum Medical Care

Latar Belakang Penyakit pada Penggunaan Transfusi Komponen Darah pada Anak

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