The epidemiology and severity of respiratory viral infections in a tropical country: Ecuador, 2009–2016

Caini, Saverio; Mora, Doménica de; Olmedo, Maritza; Portugal, Denisses; Becerra, M.A. Ortega; Mejía, Marcela; Pacurucu, María C.; Ojeda, Jenny; Bonaccorsi, Guglielmo; Lorini, Chiara; Paget, John; Bruno, Alfredo

doi:10.1016/j.jiph.2018.12.003

Cited by 27 publications

(41 citation statements)

References 35 publications

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“…20,21 The absence of significant differences in the influenza detection between males and females was consistent with previous studies. 11,17 Gender was also not a risk factor for the non-influenza respiratory infections, except for RSV and HRV. The significantly higher presence of RSV noted in this study in females under 5 years old was in contrast with earlier reported male predominance.…”

Section: F I G U R E 3 Seasonal Distribution Of Respiratory Viruses Imentioning

confidence: 89%

“…The finding of RSV and influenza as leading respiratory viruses was consistent with studies in Thailand and Ecuador, but in contrast with results from Gabon, where RSV and influenza were preceded by AdV and PIV. [11][12][13] The actual RSV burden could still be underestimated, because the customary ILI/SARI inclusion criteria are not optimal for particular identification of RSV cases, which often present without fever.…”

Section: Discussionmentioning

confidence: 99%

“…18 The observation in Suriname of delayed or less intense RSV peaks during influenza epidemics substantiated the phenomenon of viral interference, a tendency also documented in Ecuador and Hong Kong. 11,19 The exact mechanism of viral interference is still unknown, but it has been postulated that prolonged shedding from the primary virus infection could provide temporary immune protection against infection by another respiratory virus, but an existing competition of these two viruses for the same ecological niche could also account for the low co-infection rate and the observed displacement between these two viruses. 20,21 The absence of significant differences in the influenza detection between males and females was consistent with previous studies.…”

Section: F I G U R E 3 Seasonal Distribution Of Respiratory Viruses Imentioning

confidence: 99%

“…In concordance with global data, influenza morbidity rates varied among patients from different age groups and young children were the least likely to be positive for influenza. 11,17 Differences in median age and morbidity rates are generally impacted by study population, study period, immune status, risk of exposure, and health system, but it should be noted that the numbers from Suriname were also influenced by the lack of influenza vaccination of children and elderly persons.…”

Section: F I G U R E 3 Seasonal Distribution Of Respiratory Viruses Imentioning

confidence: 99%

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Epidemiology of respiratory viruses in patients with severe acute respiratory infections and influenza‐like illness in Suriname

Grunberg¹,

Sno²,

Adhin

2020

Influenza Resp Viruses

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Section: F I G U R E 3 Seasonal Distribution Of Respiratory Viruses Imentioning

confidence: 89%

Section: Discussionmentioning

confidence: 99%

Section: F I G U R E 3 Seasonal Distribution Of Respiratory Viruses Imentioning

confidence: 99%

Section: F I G U R E 3 Seasonal Distribution Of Respiratory Viruses Imentioning

confidence: 99%

See 2 more Smart Citations

Epidemiology of respiratory viruses in patients with severe acute respiratory infections and influenza‐like illness in Suriname

Grunberg¹,

Sno²,

Adhin

2020

Influenza Resp Viruses

View full text Add to dashboard Cite

show abstract

“…In our study, after adjusting for confounders, we found that the severity of RSV-p and Flu-p were not the same. FluA-p was more severe than both RSV-p and FluB-p. Caini and colleagues [44] analyzed the severity of respiratory viral infections in Ecuador from 2009 to 2016 and found that after adjusting for age group, gender, year, type of surveillance scheme and region, the risk of death for patients infected with A (H1N1) pdm09 was 1. Our study did compare the outcomes of FluB-p and RSV-p, and found the severity of the two infections to be similar.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Clinical Characteristics and Outcomes between Respiratory s yncytial Virus and Influenza-related Pneumonia in China from 2013 to 2019

Chen

Han

et al. 2020

Preprint

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Background: Differences in the clinical features and outcomes between syncytial virus-related (RSV-p) and influenza-related pneumonia (Flu-p) are largely unknown. We aimed to compare clinical characteristics and severity between adults with the two conditions . Methods: A total of 127 patients with RSV-p, 693 patients with influenza A-related pneumonia (FluA-p) and 386 patients with influenza B-related pneumonia (FluB-p) were retrospectively reviewed from 2013 through 2019 in five teaching hospitals in China. Results: A multivariate logistic regression model indicated that age ≥ 50 years, cerebrovascular disease, chronic kidney disease, solid malignant tumor, nasal congestion, myalgia, sputum production, respiratory rates ≥ 30 beats/min, lymphocytes < 0.8×109/L and blood albumin < 35 g/L were predictors that differentiated RSV-p from Flu-p. After adjusting for confounders, a multivariate logistic regression analysis confirmed that, relative to RSV-p, FluA-p (OR 2.313 , 95% CI 1.377 - 3.885, p = 0.002) incurred an increased risk for severe outcomes, including invasive ventilation, ICU admission, and 30-day mortality. FluB-p (OR 1.630 , 95% CI 0.958 - 2.741, p = 0.071) was not associated with increased risk. Conclusions: The severity of RSV-p was less than that of FluA-p, but was comparable to FluB-p. Some clinical variables were useful for discriminating RSV-p from Flu-p.

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Epidemiology of human adenovirus associated with respiratory infection in southern Brazil

Pscheidt

Gregianini

Martins

et al. 2020

Reviews in Medical Virology

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Human adenoviruses (HAdVs) are associated with respiratory infection in the human population worldwide, but HAdV is underreported and less studied than other respiratory viruses. We investigated HAdV in patients with respiratory infection in Rio Grande do Sul (RS), Brazil, between 2004 and 2018. The frequency and seasonality of HAdV, clinical symptoms and underlying diseases were analysed.Respiratory samples from outpatients with acute respiratory illness (ARI) who attended sentinel units and from inpatients with severe acute respiratory infection (SARI) were collected for HAdV detection by immunofluorescence assay; demographic and clinical data were analysed. In total, 43,514 cases of respiratory infection were analysed, of which 8,901 were ARI (20.5%), and 34,613 (79.5%) were SARI. Respiratory viruses were detected in 35.8% of the cases. The frequency of HAdV in relation to respiratory viruses was 2.8%. HAdV circulated year-round, with higher frequency during winter and early spring; increases in the average monthly temperature were associated with decreases in HAdV infections (p ¼ 0.013). Most hospitalized patients with HAdV were male (p ¼ 0.003). HAdV infection showed association with age (p < 0.001), and children between 1 and 5 years old accounted for 30.8% of the outpatients, whereas among cases of SARI, 88.2% were paediatric patients. Among inpatients with HAdV, 3% died, and of these, the majority had at least one underlying condition, such as cardiopathy and immunosuppression. HAdV infection of the respiratory tract causes morbidity and mortality, and individuals with heart diseases and the immunocompromised are at higher risk of fatality.

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The epidemiology and severity of respiratory viral infections in a tropical country: Ecuador, 2009–2016

Cited by 27 publications

References 35 publications

Epidemiology of respiratory viruses in patients with severe acute respiratory infections and influenza‐like illness in Suriname

Epidemiology of respiratory viruses in patients with severe acute respiratory infections and influenza‐like illness in Suriname

Comparison of Clinical Characteristics and Outcomes between Respiratory s yncytial Virus and Influenza-related Pneumonia in China from 2013 to 2019

Epidemiology of human adenovirus associated with respiratory infection in southern Brazil

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