Antidepressants for Elderly People 1989
DOI: 10.1007/978-1-4899-3436-9_3
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The epidemiology and natural history of depression in old age

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Cited by 8 publications
(6 citation statements)
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“…Correlations between the BDI (completed by subject) and the BAS andHDRS in 1985 and1989 ranged from 0.75 to 0.92; in 1987 the respective correlations were 0.36 and 0.40 (p < 0.05).…”
Section: Reliability and Cutoff Pointsmentioning
confidence: 94%
“…Correlations between the BDI (completed by subject) and the BAS andHDRS in 1985 and1989 ranged from 0.75 to 0.92; in 1987 the respective correlations were 0.36 and 0.40 (p < 0.05).…”
Section: Reliability and Cutoff Pointsmentioning
confidence: 94%
“…Clinical trial evidence (mostly using comparators rather than placebo) suggests a response rate to most antidepressants of about 60 per cent, a figure similar to that found earlier in life (Katona, 1993). Side-effects and the problems associated with comorbid medical illness or its treatment are however more often an issue in routine practice with older patients.…”
Section: What Options Are Available For Acute Management?mentioning
confidence: 93%
“…The most important changes concern liver and kidney function. Although the variability across subjects is large [130,131], the changes generally result in an increase in the serum levels of the substance [132] and a larger half-life. Additionally, as age increases, the ratio of fat to muscle also increases [133] and this results in an increase in the volume of distribution of most psychotherapeutic agents.…”
Section: Therapeutic Interventionmentioning
confidence: 99%