The epidemiology and natural history of depression in old age

Katona, Cornelius

doi:10.1007/978-1-4899-3436-9_3

Cited by 8 publications

(6 citation statements)

References 30 publications

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“…Correlations between the BDI (completed by subject) and the BAS andHDRS in 1985 and1989 ranged from 0.75 to 0.92; in 1987 the respective correlations were 0.36 and 0.40 (p < 0.05).…”

Section: Reliability and Cutoff Pointsmentioning

confidence: 94%

The botany survey: A longitudinal study of depression and cognitive impairment in an elderly population

Snowdon

Lane²

1995

Int J Geriat Psychiatry

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SUMMARYAn 8-year-long longitudinal study of elderly people in Botany (Sydney) has provided data on the prevalence, incidence and outcome of cognitive impairment and depression in this population. In 1985, a random sample of 146 persons aged 65 years or more, living in their own Lomes, were assessed using the Brief Assessment Schedule, depression ratings and cognitive tests. Follow-up interviews were conducted after 2, 4, 6 and 8 years. Data from separate hostel and nursing home studies were used when estimating prevalence rates. The estimated prevalence and annual incidence of definite dementia in Botany were, respectively, 14% (3.5% severe) and 2.5%. Among elderly people living at home the prevalence of definite dementia was 11%; 23% of our community sample suffered dementia during the 8 years. The prevalence and minimum annual incidence of depressive disorders were, respectively, 12.5% and 2.0%. Among those living at home the prevalence was 12.3%. Dementia was associated with a high mortality rate, but the apparently increased mortality of depressed subjects did not reach significance, probably because numbers were relatively small; a high proportion of the deceased had comorbid cognitive impairment. Some depressions eventually remitted.

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“…Correlations between the BDI (completed by subject) and the BAS andHDRS in 1985 and1989 ranged from 0.75 to 0.92; in 1987 the respective correlations were 0.36 and 0.40 (p < 0.05).…”

Section: Reliability and Cutoff Pointsmentioning

confidence: 94%

The botany survey: A longitudinal study of depression and cognitive impairment in an elderly population

Snowdon

Lane²

1995

Int J Geriat Psychiatry

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“…Clinical trial evidence (mostly using comparators rather than placebo) suggests a response rate to most antidepressants of about 60 per cent, a figure similar to that found earlier in life (Katona, 1993). Side-effects and the problems associated with comorbid medical illness or its treatment are however more often an issue in routine practice with older patients.…”

Section: What Options Are Available For Acute Management?mentioning

confidence: 93%

Detecting and managing depression in older people

Katona

1995

Hum. Psychopharmacol. Clin. Exp.

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“…The most important changes concern liver and kidney function. Although the variability across subjects is large [130,131], the changes generally result in an increase in the serum levels of the substance [132] and a larger half-life. Additionally, as age increases, the ratio of fat to muscle also increases [133] and this results in an increase in the volume of distribution of most psychotherapeutic agents.…”

Section: Therapeutic Interventionmentioning

confidence: 99%