The epidemiological and clinical profile of COVID-19 in children: Moroccan experience of the Cheikh Khalifa University Center

Chekhlabi, Nabila; Kettani, Chafik El; Haoudar, Amal; Bahlaoui, A.; Mahi, M.; Ettair, Said; Dini, N.

doi:10.11604/pamj.supp.2020.35.2.23571

Cited by 12 publications

(14 citation statements)

References 16 publications

(16 reference statements)

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“…This may have introduced admission bias and selection bias, so we cannot rule out the influence of other confounding factors. The sample sizes for two studies 9,17 were relatively small, so the test efficiency may be insufficient. Also, data collected in most of the included studies did not include laboratory findings; hence, it was difficult to analyze the clinicopathological characteristics of the disease in patients across Africa.…”

Section: Discussionmentioning

confidence: 99%

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Clinical characteristics of 4499 COVID‐19 patients in Africa: A meta‐analysis

Olumade

Uzairue

2021

Journal of Medical Virology

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The novel coronavirus disease-2019 (COVID-19) pandemic that started in December 2019 has affected over 95 million people and killed over 2 million people as of January 19, 2021. While more studies are published to help us understand the virus, there is a dearth of studies on the clinical characteristics and associated outcomes of the severe acute respiratory syndrome coronavirus 2 on the African continent. We evaluated evidence from previous studies in Africa available in six databases between January 1 and October 6, 2020. Metaanalysis was then performed using Open-Meta Analyst and Jamovi software. A total of seven studies, including 4499 COVID-19 patients, were included. The result of the meta-analysis showed that 68.8% of infected patients were male.Common symptoms presented (with their incidences) were fever (42.8%), cough (33.3%), headache (11.3%), and breathing problems (16.8%). Other minor occurring symptoms included diarrhea (7.5%) and rhinorrhea (9.4%). Fatality rate was 5.6%. There was no publication bias in the study. This study presents the first description and analysis of the clinical characteristics of COVID-19 patients in Africa. The most common symptoms are fever, cough, and breathing problems.

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Section: Discussionmentioning

confidence: 99%

“…A total of 1065 records were identified during literature retrieval from databases. A total of seven studies involving 4499 COVID-19 patients were included in this meta-analysis 8,9,15,15,[17][18][19][20] (Figure 1 and Table 1).…”

Section: Literature Retrieval and Article Characteristicsmentioning

confidence: 99%

Clinical characteristics of 4499 COVID‐19 patients in Africa: A meta‐analysis

Olumade

Uzairue

2021

Journal of Medical Virology

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“…This may have introduced admission bias and selection bias, so we cannot rule out the influence of other confounding factors. The sample sizes for two studies 9,18 were relatively small, so the test efficiency may be insufficient. Also, data collected in most of the included studies did not include laboratory findings, hence, it was difficult to analyze the clinicopathological characteristics of the disease in patients across Africa.…”

Section: Discussionmentioning

confidence: 99%

“…A total of 1065 Records were identified during literature retrieval from databases. A total of 7 studies involving 4490 COVID-19 patients were included in this meta-analysis 8,9,15,[18][19][20][21] ( Figure 1 and Table 1). All studies included in this meta-analysis were conducted in African countries.…”

Section: Literature Retrieval and Articles Characteristicsmentioning

confidence: 99%

Clinical characteristics of 4490 COVID-19 patients in Africa: A meta-analysis

Olumade

Uzairue

2020

Preprint

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Introduction: The novel coronavirus disease-2019 (COVID-19) pandemic that started in December 2019 has affected over 39 million people and killed over 1.1 million people. While more studies are published to help us understand the virus, there is a dearth of studies on the clinical characteristics and associated outcomes of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) on the African continent. Methods: We evaluated evidence from previous studies in Africa available in six databases between January 1 and October 6, 2020. Meta-analysis was then performed using Open-Meta Analyst software. Results: A total of seven studies including 4490 COVID-19 patients were included. The result of the meta-analysis showed 68.8% of infected patients were male. Common symptoms presented (with their incidences) were fever (42.8%), cough (33.3%), headache (11.3%), breathing problems (16.8%). Other minor occurring symptoms included diarrhea (7.5%), and rhinorrhea (9.4%). Fatality rate was 5.6%. Conclusion: This study presents the first description and analysis of the clinical characteristics of COVID-19 patients in Africa. The most common symptoms are fever, cough and breathing problems.

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“…Fewer cases of coronavirus disease 2019 (COVID-19) have been diagnosed in children than in adults, and most of them have been mild. In Morocco, children got COVID-19 infection from family members, and they seem to have a milder illness than adults, with mild symptoms and a good short-term prognosis [ 1 ]. However, since mid-April 2020, multiple case clusters of what has been termed multisystem inflammatory syndrome in children (MIS-C) have been reported from different countries and, as of October 1, 2020, there were 1,027 cases reported in the United States with a total of 20 deaths [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Severe SARS-CoV-2 Infection: A Multisystem Inflammatory Syndrome in Moroccan Children

Haoudar¹,

Chekhlabi²,

Eljazouly³

et al. 2021

Cureus

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Until October 2020, children seem to have a mild form of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in Morocco. Since April 2020, a new entity of multisystem inflammatory syndrome in children associated with SARS-CoV-2 infection was reported in England, Italy, France, and the United States. This syndrome has similarities with the most frequent vasculitis in children, Kawasaki disease. Here, we describe the features and outcome of the first five cases of Kawasaki-like multisystem inflammatory syndrome in Moroccan children triggered by the SARS-CoV-2. The median age of the children was 7.8 years; three of them were boys. Criteria for Kawasaki disease were met in all of them with a complete presentation. Three patients required admission to a critical care unit with multi-organ failure in one of them, but no mortality occurred. They all received intravenous immunoglobulin (IVIG), a high dose of aspirin, methylprednisolone, and supportive therapy. Coronavirus 2019 disease (COVID-19) infection in children may be life-threatening; rigorous monitoring for several weeks is required in any positive child or living in a family cluster.

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The epidemiological and clinical profile of COVID-19 in children: Moroccan experience of the Cheikh Khalifa University Center

Cited by 12 publications

References 16 publications

Clinical characteristics of 4499 COVID‐19 patients in Africa: A meta‐analysis

Clinical characteristics of 4499 COVID‐19 patients in Africa: A meta‐analysis

Clinical characteristics of 4490 COVID-19 patients in Africa: A meta-analysis

Severe SARS-CoV-2 Infection: A Multisystem Inflammatory Syndrome in Moroccan Children

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