Hodgkin's Lymphoma (HL) is a heterogeneous group with several histological types. It is more common in young adults but its frequency varies according to geographical location. This study is going to establish the epidemiological, histopathological and immunohistochemical profile of Hodgkin's lymphoma in the Democratic Republic of Congo (DRC). We conducted a retrospective transversal descriptive study in 4 histopathology laboratories. 93 paraffin blocks were cut between 3 and 5µm and stained with hematoxylin-eosin. 10 paraffin blocks were selected for immunohistochemistry with CD15, CD30, PAX5 and LMP1 antibodies. The HL represents 24.73% of all lymphomas and 1.06% of all cancers. Only one age group was more affected, between 20 and 30 years of age. Males are more affected, with a sex ratio of 1.2:1. The majority of HL are lymph node lymphomas (91.4%). Classical type HL (HLc) is the most predominant, with 96.8%. The histological type with mixed cellularity (HLcMC) is predominant with 51.1%, followed by sclerodular (HLcSN) with 36.7%. HLcMC is more common in all age groups, except in the1st decade. HL is associated with tuberculosis in 3% of cases. The majority (58%) of HLc were grade 2. Tumour cells expressed CD30 and CD15 in 20%, PAX5 in 60% and LMP1 in 0%. In the DRC, HL is more common in young people, men are at greater risk than women, and the histological type with mixed cellularity is more common. Reed Sternberg cells express PAX5 more than CD15 and CD20.