The EORTC quality of life questionnaire for patients with colorectal cancer: EORTC QLQ-CR29 validation study for Spanish patients

Arrarás, Juan Ignacio; Suárez, Javier; Vega, F. Arias de la; Vera, Ruth; Asin, Gemma; Arrazubi, Virginia; Rico, M.; Teijeira, Lucía; Azparren, Jaione

doi:10.1007/s12094-011-0616-y

Cited by 51 publications

(79 citation statements)

References 14 publications

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“…Eighteen suitable datasets were obtained [27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44]. Table 1 summarises their characteristics and the number of observations each contributed to various psychometric analyses.…”

Section: Resultsmentioning

confidence: 99%

QLU-C10D: a health state classification system for a multi-attribute utility measure based on the EORTC QLQ-C30

et al. 2016

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Abstract:Purpose: To derive a health state classification system (HSCS) from the cancerspecific quality of life questionnaire, the EORTC QLQ-C30, as the basis for a multiattribute utility instrument.Methods: The conceptual model for the HSCS was based on the established domain structure of the QLQ-C30. Several criteria were considered to select a subset of dimensions and items for the HSCS. Expert opinion and patient input informed a priori Powered by Edit orial Manager® and ProduXion Manager® from Aries Syst em s Corporat ionselection of key dimensions. Psychometric criteria were assessed via secondary analysis of a pooled dataset comprising HRQOL and clinical data from 2616 patients from eight countries and a range of primary cancer sites, disease stages, and treatments. We used confirmatory factor analysis (CFA) to assess the conceptual model's robustness and generalisability. We assessed item floor effects (>75% observations at lowest score), disordered item response thresholds, coverage of the latent variable and differential item function (DIF) using Rasch analysis. We calculated effect sizes for known group comparisons based on disease stage and responsiveness to change. Seventy-nine cancer patients assessed the relative importance of items within dimensions.Results: CFA supported the conceptual model and its generalizability across primary cancer sites. After considering all criteria, 12 items were selected representing 10 dimensions: physical functioning (mobility), role functioning, social functioning, emotional functioning, pain, fatigue, sleep, appetite, nausea, bowel problems.

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Section: Resultsmentioning

confidence: 99%

QLU-C10D: a health state classification system for a multi-attribute utility measure based on the EORTC QLQ-C30

et al. 2016

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“…Our data mainly showed lower Cronbach’s α coefficients than those in a similar study by Nowak et al[8], particularly in the urinary frequency dimension (0.363-0.608). Of note, in the studies by Arraras et al[5], Nowak et al[8] and Arraras Urdaniz et al[24], Cronbach’s α coefficients below 0.7 were also obtained for the abdominal pain and blood and mucus in the stool dimensions. The differences between our findings and those of previous studies may be due to differences in the perceptions of quality of life in patients from different regions; however, the differences were still in the acceptable range.…”

Section: Discussionmentioning

confidence: 99%

“…The questionnaires ask for all items in the past week except those pertaining to sexuality, which request the patients to evaluate the items in the past four weeks. Similar to the EORTC QLQ-C30, the QLQ-CR29 has a Likert scale of four response categories (item 48 requires a yes or no answer)[5,8,9]. All patient-rated scores are linearly converted into a scale from 0 to 100 for both the QLQ-C30 and QLQ-CR29[7,15].…”

Section: Methodsmentioning

confidence: 99%

Validation of the chinese version of the EORTC QLQ-CR29 in patients with colorectal cancer

Lin¹,

Zhang²,

Wu³

et al. 2017

WJG

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AIMTo assess the validity and reliability of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Colorectal Cancer 29 (EORTC QLQ-CR29) in Chinese patients with colorectal cancer (CRC).METHODSFrom March 2014 to January 2015, 356 patients with CRC from four different hospitals in China were enrolled in the study, and all patients self-administered the EORTC QLQ-CR29 and the quality of life core questionnaire (EORTC QLQ-C30). Evaluation of the scores was based on the Karnofsky Performance Scale (KPS). The reliability and validity of the questionnaires were assessed by Cronbach’s α coefficient, the Spearman correlation test and Wilcoxon rank sum test.RESULTSThe EORTC QLQ-CR29 showed satisfactory reliability (α > 0.7), although the urinary frequency and blood and mucus in stool dimensions had only moderate reliability (α = 0.608). The multitrait scaling analyses showed good convergent (r > 0.4) and discriminant validity. Significant differences were obtained for each item in the different KPS subgroups (KPS ≤ 80; KPS > 80). Body image and most single-item dimensions showed statistically significant differences in patients with a stoma compared with the rest of the patients.CONCLUSIONThe EORTC QLQ-CR29 exhibits high validity and reliability in Chinese patients with CRC, and can therefore be recommended as a valuable tool for the assessment of quality of life in these patients.

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“…All ratings given to the nine instruments that were assessed on this property (version 3 of QLQ-C30 [27,29,30,65,66], QLQ-SWB36 [53], QLQ-CR38 [21e27], QLQ-CR29 [31,54], FACT-C [23,27,33,34,55,59e61], MSAS-SF [56], CMSAS [56], SRQS [57], and MSKCC Bowel Function [40,41]) were unknown as inadequate information was provided by these studies.…”

Section: Cross-cultural Validitymentioning

confidence: 99%

Systematic review recommends the European Organization for Research and Treatment of Cancer colorectal cancer–specific module for measuring quality of life in colorectal cancer patients

Wong

Chen

et al. 2015

Journal of Clinical Epidemiology

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The EORTC quality of life questionnaire for patients with colorectal cancer: EORTC QLQ-CR29 validation study for Spanish patients

Abstract: The EORTC QLQ-CR29 is a reliable and valid instrument when applied to a sample of Spanish rectal cancer patients. These results are in line with those of the EORTC validation study.

Cited by 51 publications

References 14 publications

QLU-C10D: a health state classification system for a multi-attribute utility measure based on the EORTC QLQ-C30

QLU-C10D: a health state classification system for a multi-attribute utility measure based on the EORTC QLQ-C30

Validation of the chinese version of the EORTC QLQ-CR29 in patients with colorectal cancer

Systematic review recommends the European Organization for Research and Treatment of Cancer colorectal cancer–specific module for measuring quality of life in colorectal cancer patients

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