The enzymatic degradation of commercial biodegradable polymers by some lipases and chemical degradation of them

Abstract

Biodegradable polyesters, poly(butylene succinate adipate) (PBSA), poly(butylene succinate) (PBS), poly(ethylene succinate) (PES), poly(butylene succinate)/poly(caprolactone) blend (HB02B) and poly(butylene adipate terephthalate) (PBAT), were evaluated about degradability for enzymatic degradation by lipases and chemical degradation in sodium hydroxide solution. In enzymatic degradation, PBSA was the most degradable by lipase PS, on the other hand, PBAT containing aromatic ring was little degraded by eleven kinds of lipases. In 1N NaOH solution, degradation rate of PES with ethylene unit was extremely fast, in comparison with other polyesters. Interestingly the degradation rate of PBSA in enzymatic degradation by lipase PS was faster than in chemical degradation.

Thermal and Mechanical Properties of Sustainable Composites Reinforced with Natural Fibers

“…On the contrary, biodegradable polymers degrade easily owing to action of microorganisms (bacteria, fungi, and microflora), when disposed in bioactive environments. Their polymer chains may also be cleaved by enzymatic processing and chemical hydrolysis [2][3][4].…”

A systems approach to modeling drug release from polymer microspheres to accelerate in vitro to in vivo translation

“…We have postulated that reactive oxygen species (ROS)-mediated degradation of the polymer matrix is responsible for accelerated in vivo degradation and drug release, however it is known that certain enzymes such as lipases, lysozymes and esterases exhibit biodegradative activity toward biodegradable polymers 48,31,49,50,30,32,29,51,52 . Here we employ our model to study the potential effects of enzymatic degradation under the assumption that degradative enzymes would have the same transportation kinetics and correlations 1 governing their diffusion into a microparticle as drug releasing from the microparticle.…”

Furanic‐Aromatic Copolyesters by Interchange Reactions between Poly(ethylene terephthalate) and Poly[ethylene 5,5′‐isopropylidene‐bis(2‐furoate)]

“…[2,3] During the last decade, a number of studies have been published on the synthesis and biodegradability of aliphatic-aromatic copolyesters. [4][5][6][7][8][9][10][11][12][13][14] Such copolyesters are usually synthesized by the conventional polycondensation of monomers, but can also be synthesized by ester interchange reactions between homopolyesters, such as PET, and either aliphatic monomers or aliphatic polyesters. The chemical modification of PET by the incorporation of aliphatic units in polymer chains in order to obtain biodegradable aliphatic-aromatic copolyesters, therefore, seems to be a promising approach for PET chemical recycling.…”