1986
DOI: 10.1016/0160-4120(86)90064-4
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The environmental protection agency's research program on total human exposure

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Cited by 19 publications
(4 citation statements)
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“…Though a CSF could have been used for the MESH study, in general, few health-based values (such as a RfD, CSF, reference concentration or BEI) are available to put biomonitoring results into context [ 5 ]. A Transparent, Bi-directional Discussion about Risk Assessment with Communities—Current knowledge of exposure and dose is limited for most contaminants of concern and since the human health risk model is sequential, the lack of accurate information can severely weaken the ability to assess risk and protect human health [ 68 ]. These data gaps are more pronounced in children’s exposure assessment (e.g., [ 69 ]).…”
Section: Discussionmentioning
confidence: 99%
“…Though a CSF could have been used for the MESH study, in general, few health-based values (such as a RfD, CSF, reference concentration or BEI) are available to put biomonitoring results into context [ 5 ]. A Transparent, Bi-directional Discussion about Risk Assessment with Communities—Current knowledge of exposure and dose is limited for most contaminants of concern and since the human health risk model is sequential, the lack of accurate information can severely weaken the ability to assess risk and protect human health [ 68 ]. These data gaps are more pronounced in children’s exposure assessment (e.g., [ 69 ]).…”
Section: Discussionmentioning
confidence: 99%
“…Concentrations measured at fixed monitoring sites or concentration surrogates (such as nearby traffic counts) are used to derive exposures at the residence locations (Huang and Batterman 2000 ; Meng et al 2007 ; von Klot et al 2009 ). Although this is a relatively simple and generalizable approach that can be applied in the context of available data, it is recognized that human activity patterns may be particularly important for explaining exposure variation (Klepeis et al 2001 ; National Center for Environmental Assessment et al 2011 ; Ott et al 1986 ). Hence, exposure error and misclassification are concerns, with potential outcomes of inaccurate health and environmental impact assessments and policy interventions (Huang and Batterman 2000 ; Krzyzanowski 1997 ; Özkaynak et al 1986 ; Sheppard et al 2012 ; Thomas et al 1993 ; Zeger et al 2000 ).…”
Section: Introductionmentioning
confidence: 99%
“…The exact time of day recorded by the PEM when combined with activity data allowed microenvironmental CO concentrations to be related to human activities, thus providing a complete CO exposure profile of each person carrying the instrument. 13 The lowest detectable level of the PEM was approximately 1 ppm. Readings between 0.5 and 1.5 ppm were rounded to 1 ppm; CO concentration levels smaller than 0.5 ppm were recorded as 0 ppm.…”
Section: Denver Pem Data Basementioning
confidence: 93%
“…There are two "primary" (health-based) CO NAAQS: a 1-hr 40 mg/m 3 (35 ppm) and an 8-hr 10 mg/m 3 (9 ppm). These standards were first promulgated in 1971 (36 FR 8186; April 30, 1971) and were reaffirmed in both 1985 (50 FR 37484; Sept. 13,1985) and 1994 (59 FR 38906; August 1, 1994). As part of its standard review activities, the EPA undertakes an exposure modeling analysis using the pNEM/CO model.…”
Section: Introductionmentioning
confidence: 95%